Abstract: Orthogonal experimental design was adopted to optimize the method for extraction of pueraria flavonoid from pueraria lobata.The results indicated that the optimal extraction condition was 5-fold volume of 90% alcohol,refluxing extraction for 2 h,and extraction for 3 times.The extraction yield of general flavonoid was 7.43%.Qualitative experiment showed that the main flavonoid compounds from pueraria lobata were isoflavone compounds.Pueraria flavonoid can be developed into herbal drugs for the treatment of cardiovascular diseases or the relevant health food.

Key words: pueraria lobata, flavonoid, extraction, application