Journal of Jishou University(Natural Sciences Edition)

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Optimization of Ultrasonic-Assisted Extraction of Flavonoids from Artemisia Princeps Pamp. by Response Surface Methodology

ZHANG Shan,XIAO Juan,SONG Xiaohui,XIONG Lizhi   

  1. (College of Biology and Environment Sciences,Jishou University,Jishou 416000,China)
  • Online:2018-03-25 Published:2018-04-28


The effects were studied of ratio of material-to-liquid,extraction time,extraction temperature,ethanol volume fraction and ultrasonic power on the extraction rate of flavonoids from Artemisia princeps Pamp..Based on single factor experiments,the method of response surface methodology was used to optimize the extraction process of flavonoids.The results showed that the optimum conditions obtained through response surface methodology were as follows:the material-to-liquid 1∶20 (g∶mL),the extraction time 50 min,the extraction temperature 65 ℃ and the ultrasonic power 200 W.Under the optimal condition,the extraction rate of flavonoids was 2.493%.

Key words: Artemisia princeps Pamp., flavonoids, extraction, ultrasonic, response surface

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