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    Interaction Between the Digital Economy and Rural Revitalization:A Case Study of the Urban Agglomeration of the Yangtze River Economic Belt
    LIU Junqiao, ZHANG Yong, WANG Chen
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 86-91.   DOI: 10.13438/j.cnki.jdzk.2024.04.013
    Abstract485)      PDF(pc) (1236KB)(293)       Save
    Panel data of 110 cities in the Yangtze River Economic Belt from 2011 to 2020 are selected,and rural revitalization,digital foundation,industrial digitization and digital industrialization are included in the research framework,and the interaction between rural revitalization and the other three is empirically studied by using panel vector autoregressive model.The research results show that rural revitalization will constrain the development of digital foundation and promote the development of digital industrialization;the role of digital foundation and digital industrialization on rural revitalization is shown as constraining first and then promoting;rural revitalization and industrial digitization will promote each other.Based on this,suggestions are made to strengthen the development of digital infrastructure and local characteristic industries,implement differentiated development strategies,and play the promoting role of core cities.
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    Advances in Metabolic Related Fatty Liver Disease Complicated with Type 2 Diabetes Mellitus
    LI Yuan, XIANG Ping, LI Xuefeng, PENG Xia
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 91-96.   DOI: 10.13438/j.cnki.jdzk.2024.03.013
    Abstract392)      PDF(pc) (583KB)(179)       Save
    Metabolic Associated Fatty Liver Disease (MAFLD) and Type 2 Diabetes Mellitus (T2DM) are highly prevalent worldwide.More than 70% of patients with T2DM may develop MAFLD,and patients with MAFLD have a risk of diabetes that is about 5 times higher than the general population,both of which are serious threats to human health.When MAFLD is combined with T2DM,it is more difficult to control T2DM,MAFLD is more likely to deteriorate,and patients have a higher incidence of cardiovascular disease,malignant tumors,and a greater risk of death.In this study,the epidemiology,pathogenesis,risk factors and treatment methods of MAFLD complicated with T2DM are systematically described,aiming to improve the understanding of MAFLD complicated with T2DM and provide better guidance for  clinical diagnosis and treatment.
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    Application Effect of Continuous Nursing in Interventional Therapy of Patients with Coronary Heart Disease
    XIA Yalan, LONG Jie, WANG Yang, ZENG Zhi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 82-85.   DOI: 10.13438/j.cnki.jdzk.2024.04.012
    Abstract376)      PDF(pc) (375KB)(230)       Save
    In order to explore the effect of continuous nursing in interventional therapy (PCI) for patients with coronary heart disease (CHD),80 CHD patients who underwent PCI between January 2024 and April 2024 were selected as the study subjects.Patients were randomly divided into observation group (conventional nursing combined with continuous nursing mode) and control group (conventional nursing mode) with 40 cases in each group.The quality of life score,negative emotion score and complication rate of patients before and after nursing were compared.The results showed that the quality of life score after nursing in the observation group was significantly higher than that in the control group,and the difference between groups was statistically significant (P<0.05).The negative emotion score of the observation group after nursing was significantly lower than that of the control group,and the difference between groups was statistically significant (P<0.05).The incidence of adverse reactions after nursing in the observation group was significantly lower than that in the control group,and the difference between groups was statistically significant (P<0.05).For CHD patients undergoing PCI,continuous nursing has shown positive effects on improving quality of life,alleviating negative emotions,and reducing the incidence of complications.
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    Genetic Diversity of Rhodeus Ocellatus from Lancang River of Yunnan
    LI Rong, NING Yanhong, MENG Feiyan, XU Weijiang, TIAN Hanji, FAN Lixian
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 50-58.   DOI: 10.13438/j.cnki.jdzk.2024.04.008
    Abstract372)      PDF(pc) (1533KB)(326)       Save
    To investigate genetic diversity of Rhodeus ocellatus from Lancang River of Yunnan,this study applied PCR amplification and sequencing methods to determine the mitochondrial COI gene sequence fragments of 10 R. ocellatus samples from Xishuangbanna.Additionally,we combined with the homologous sequence of COI gene of six Rhodeus species from GenBank database to execute the genetic diversity,genetic distance and phylogenetic analyses.Sequence analyses showed that the COI gene sequence fragments was 657 bp,the base composition A+T content (52.5%) was larger than the G+C content (47.5%),and there were 21 variable sites and 4 haplotypes.The haplotype diversity of R. ocellatus was 0.711,the nucleotide diversity was 0.008 2,the average nucleotide difference was 5.400,and the Tajima's D value was -1.353 78 (P>0.10).The minimum genetic distance between our R. ocellatus samples and R. ocellatus from Baoshan city was 0.005,and the maximum genetic distance between R. ocellatus samples and R. notatus was 0.196.Phylogenetic analysis showed that R. ocellatus samples were clustered into a monophyletic branch with the same sequence published from Baoshan city with high bootstrap value (100%).Furthermore,the R. amarus,R. colchicus and R. meridionalis samples clustered together as a monophyletic clade,while R. notatus and R. uyekii samples were gathered to form a monophyletic branch.
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    Preparation and Electrochemical Properities of Cathode Material Li3V2-xCox(PO4)3 for Aqueous Hybrid Battery
    WANG Wei, PI Shengdong, WANG Cheng, SUN Yan, XIONG Lizhi, XIANG Yanhong
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 67-75.   DOI: 10.13438/j.cnki.jdzk.2024.04.010
    Abstract346)      PDF(pc) (11785KB)(208)       Save
    In this design,Li3V2-xCox(PO4)3 materials were synthesized by freeze-drying assisted sol-gel method,with ammonium metavanadate,lithium acetate dihydrate,and ammonium dihydrogen phosphate as raw materials,and cobalt acetate tetrahydrate as Co doping source.The effect of Co doping on the structural and electrochemical properties of the materials was investigated.The results show that Monoclinic crystals with good crystallinity can be obtained by freeze-drying assisted sol-gel method,and the crystal structure of lithium vanadium phosphate is not changed by proper Co doping.The positive electrode materials synthesized by freeze-drying assisted sol-gel have microporous structure.The proper amount of Co doping helps to increase the number of micropores and obtain the material with more uniform particle size.With the increase of Co doping amount,the ion diffusion rate,charge/discharge and cycling performance of the materials all presents a trend of first increasing and then decreasing,while the charge transfer impedance presents a trend of first decreasing and then increasing.When x=0.04,the electrochemical performance of the lithium vanadium phosphate cathode material is the best,the ion diffusion rate reached 8.99×10-13 cm/s,the charge transfer impedance is the lowest,233.6 Ω,and the initial discharge capacity  increases from undoped 53.4 mAh/g to 81.7 mAh/g at 2C discharge rate.After 50 weeks of 2C rate cycle,the discharge capacity retention rate is 91.11%,which is 13.54% higher than that of the undoped sample.
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    Fault Diagnosis of High-Voltage AC Transmission Lines Based on Wavelet Packet Transform and XGBoost
    PAN Min, WANG Xuming, SUN Longfei, LEI Kejun, YANG Xi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 32-40.   DOI: 10.13438/j.cnki.jdzk.2024.04.006
    Abstract326)      PDF(pc) (1842KB)(249)       Save
    In view of the short-circuit fault situation of high-voltage AC transmission line,the three-phase AC voltage and current signals are transformed into wavelet packets to extract the fault features,and then the extracted features are input into the XGBoost model for fault diagnosis.The experimental results show that the fault identification accuracy of the fault diagnosis method based on wavelet packet transform and XGBoost is 99.6% for the fault of high-voltage AC transmission line under different operating conditions.Compared with other machine learning models,this method has high accuracy.
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    Application of Simplified Thin-Layer Chromatography in the Analysis of Paulownia fortunei Leaves
    LI Ming, WANG Qingrong, LI Yuhong, GUO Hongwei, LONG Guoqing, LYU Shuang, WEI Hua
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 62-67.   DOI: 10.13438/j.cnki.jdzk.2024.06.009
    Abstract319)      PDF(pc) (11056KB)(85)       Save
    A simplified one-dimensional thin-layer chromatography (TLC) method has been established for the identification of Paulownia species leaves,including Paulownia fortunei,Paulownia elongata,Paulownia tomentosa and Paulownia kawakamii.A single-factor experiment was conducted to select the optimal two-dimensional multiple development TLC method,which was then combined with column chromatography to segment the extract.Then,the one-dimensional TLC method was employed to identify the leaves of the four Paulownia species after developing the concentrated segments.The results showed that in the two-dimensional multiple expansion,characteristic spots of Paulownia fortunei were identified.Additionally,in the one-dimensional thin layer after segmented concentration,four common characteristic spots were observed for the four Paulownia species at 254 nm,seven common spots at 365 nm,and twelve common spots after color reaction under sunlight.The differences between Paulownia fortunei and the other three species were noted:on the developed TLC plate after color reaction,the first segment of the small polar sample showed a slightly yellow spot at an Rf value of 0.5,while the third segment of the large polar sample exhibited two light pink spots at an Rf value of approximately 0~0.2.
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    Construction of Tusi World Cultural Heritage Literature Database
    LI Hongyan
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 92-96.   DOI: 10.13438/j.cnki.jdzk.2024.04.014
    Abstract277)      PDF(pc) (416KB)(241)       Save
    This paper analyzes and explores the ideas,content,methods,and significance of constructing the database of tusi world cultural heritage literature.The database construction includes processes of  literature collection and organization,content annotation and description,framework design,platform construction,data input,domain name registration,and so on.The construction of this database enables the systematic and complete presentation of world heritage Tusi literature,providing convenience for the retrieval and utilization of Tusi literature,and providing a literature basis for the protection and development of Tusi sites.
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    Spatiotemporal Evolution of Transformation Efficiency of Sci-Tech Achievements  in Local Universities of  China Based on DEA-Malmquist Model
    ZHANG Yanfei, ZHU Haiying
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 71-81.   DOI: 10.13438/j.cnki.jdzk.2024.03.010
    Abstract277)      PDF(pc) (1132KB)(195)       Save
    An empirical analysis of the spatiotemporal evolution characteristics of technical efficiency and total factor productivity change of the sci-tech achievements transformation has been carried on based on DEA-Malmquist model.The results show that the comprehensive technical efficiency of sci-tech achievements increased year by year,but the efficiency in 2017 and 2018  significantly fallen compared with that in previous years,and the efficiency index was overall low.The total factor productivity change indexes of the transformation of sci-tech achievements improved overall,but there were significant regional differences,with steady increase in central and eastern China and significant fluctuations in western China.To improve the efficiency in the transformation of sci-tech achievements in local universities,it is proposed to strengthen discipline construction,make clear the positioning of sci-tech innovation,innovate the mechanism of achievement transformation,and optimize the environment for achievement transformation.
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    Path for Ideological and Political Education in University Sports Curriculum of the New Era
    LI Yuwen
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 93-96.   DOI: 10.13438/j.cnki.jdzk.2024.05.013
    Abstract271)      PDF(pc) (332KB)(106)       Save
    In response to the problems existing in the ideological and political education in college sports courses,it is proposed that the ideological and political elements in college sports teaching should be highlighted,the ideological and cultural literacy of college sports teachers should be enhanced,the effect of diversified evaluation sports be strengthened,the integrated construction of the ideological and political system and mechanism be strengthened,the construction of distinctive sports courses with ideological and political characteristics be enhanced,the efforts to strengthen the construction of campus sports culture be intensified,and the construction of sports clubs and sports brand activities should be strengthened.Ultimately,the goal is to achieve the organic combination of ideological and political education and physical education in university sports curriculum.
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    Identification Analysis on Craspedacusta sp.from Bayue Lake in Jishou City
    YUAN Saibo, YUAN Guoqing, XIANG Ying, FENG Weisong, ZHANG Youxiang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 35-44.   DOI: 10.13438/j.cnki.jdzk.2024.03.006
    Abstract268)      PDF(pc) (6293KB)(258)       Save
    In order to strengthen the conservation and sustainable utilization of Craspedacusta,we used the methods of morphological identification and molecular biological identification to identify and analyze the Craspedacusta sp. from Bayue Lake in Jishou City of Xiangxi.The results were as follows:Diameter of umbrella was 12.4 mm.Tentacle 3~4,and the main tentacle was significantly longer than other tentacles.The gonads were cystic,and brown yellow in color.Statocysts were tubular,106~128 in number.Nematocyst warts arranged in a ring and each of ring had interval.The similarity of 18S rDNA gene sequence between Craspedacusta sp. from Bayue Lake and Craspedacusta sowerbyi of the United States (GenBank serial number MG979336.1) was the highest,which was 99.88%.The relationship between the Craspedacusta sp. from Bayue Lake in Xiangxi and Craspedacusta sowerbyi was close.Both morphological and molecular data support that the Craspedacusta sp. from Bayue Lake in the Xiangxi was Craspedacusta sowerbyi.
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    Stability and Hopf Bifurcation of a Delayed Drug Abstinence Model
    ZHANG Zizhen, ZHANG Yixue
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 1-10.   DOI: 10.13438/j.cnki.jdzk.2024.05.001
    Abstract258)      PDF(pc) (1981KB)(153)       Save
    A class of delayed Susceptible-Light-Heavy-Mentally ill-Treated-Quitted (SLHMTQ)drug rehabilitation model with bilinear contact rate was studied.The bifurcation parameter as the time delay of drug addiction relapse,the local asymptotic stability of the model and the existence of local Hopf bifurcation were investigated using the eigenvalue method.The critical time delay value for the model to generate local Hopf bifurcation was derived,and the properties of the bifurcation periodic solution were studied using the central manifold theorem.
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    Genome Based Phylogeny Analysis of Siderophore-Producing Marine Halophilic Bacterium JSM 21308
    DENG Liying, SHI Yuanjie, CHEN Jinhua, DA Chunyao, LIU Zhuxiang, CHEN Yiguang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 61-67.   DOI: 10.13438/j.cnki.jdzk.2024.05.008
    Abstract256)      PDF(pc) (2392KB)(124)       Save
    To accurately determine the systematic status of the siderophore-producing marine halophilic bacteria JSM 21308 isolated from mangrove sediment collected from the Moon Bay in Wenchang City in Hainan Province,PR China,the evolutionary status was primarily analysed based on 16S rRNA gene sequences.The draft genome was mapped,and then the exact phylogenetic relationship of strain JSM 21308 with its closely relative type strains was investigated by comparative genomics analysis based on whole-genome sequences,including comparisons of G+C content,average nucleotide identity (ANI),and digital DNA-DNA hybridization (dDDH) values,and phylogenomic analysis.The result of 16S rRNA gene sequence analysis showed that JSM 21308 belonged to the family Bacillaceae,and was most closely related to Pseudalkalibacillus hwajinpoensis SW-72T (16S rRNA gene sequence similarity,99.66%) and Alkalihalobacillus hemicentroti JSM 076093T (98.7%).These three strains formed obvious subclusters on the phylogenetic tree of 16S rRNA gene sequence,in which JSM 21308 made a separated branch.The results of comparative genomics analysis showed that the ANI and dDDH values of strain JSM 21308 and the type strain of A. hemicentroti were respectively 77.69% and 21.40%,all lower than the generally recognized threshold of bacterial species (ANI,95%~96%;dDDH,70% ).However,the ANI and dDDH values of strain JSM 21308 and A. hemicentroti JSM 076093T reached up to 99.99% and 100%,respectively.The result of phylogenomic analysis performed at the species level (70% dDDH threshold ) and subspecies level (79% dDDH threshold) also showed that strain JSM 21308 and the type strain of A. hemicentrotinot only represented the same species cluster but also the same subspecies cluster.Based on the combination of both the results of phylogenetic analysis of 16S rRNA gene sequences and comparative genomic analysis,strain JSM 21308 should be a new member of the known species of the genus Alkalihalobacillus,A. hemicentroti.
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    Automobile Anti-Lock Brake System Fuzzy Variable Structure Control
    CHEN Dezheng, WANG Shinong, GU Huangyi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 41-49.   DOI: 10.13438/j.cnki.jdzk.2024.04.007
    Abstract254)      PDF(pc) (1826KB)(226)       Save
    For the problem of insufficient use of the ground adhesion coefficient and high nonlinearity of the Anti-lock Braking System (ABS) in the process of automobile braking,a road surface recognition algorithm is designed based on Burckhardt's tyre model,and the optimal slip rate detected by the road surface recognition algorithm is fed into the fuzzy variable structure control,so as to propose a fuzzy variable structure control strategy for ABS based on road surface detection.The results of the simulation experiments show that the road surface recognition algorithm has  fast response and high accuracy;under the conditions of variational road surface,the fuzzy variable structure control reduces the braking time by 7% and the braking distance by 6% compared with the variable structure control,and the amplitude of the jitter vibration of the controller output is effectively attenuated.
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    Existence of Pulse Solutions for the Quintic Real Ginzburg-Landau Equation with Coupled Slow Diffusion Mode
    BIN Qun, OUYANG Yuting, DU Chaoxiong
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 5-10.   DOI: 10.13438/j.cnki.jdzk.2024.04.002
    Abstract251)      PDF(pc) (1006KB)(269)       Save
    Utilizing Fenichel's geometric singular perturbation theory,we transform the problem of pulse solution existence for a coupled subcritical quintic real Ginzburg-Landau equation with slow diffusion mode into a geometric perturbation scenario,showing the transversality between critical manifolds.Through the computation of the Melnikov function's zeros on the critical manifolds,the presence of homoclinic orbits is further confirmed.Ultimately,it is demonstrated that,under specific parameter conditions,the subcritical quintic Ginzburg-Landau equation with slow diffusion exhibits pulse solutions.
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    Performance Study of Modified Biochar for Phosphorus Adsorption in Water Bodies
    LI Jie, LI Bo, ZHANG Xiaodong, LI Bin, ZHOU Yingru
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 55-62.   DOI: 10.13438/j.cnki.jdzk.2024.03.008
    Abstract247)      PDF(pc) (2138KB)(266)       Save
    Modified charcoal (MCC) was made from corn cobs pretreated by NH3·H2O and impregnated with  MgCl2·6H2O.The morphology and functional groups of MCC was characterized,and its impact on phosphate phosphorus adsorption was investigated.The results showed that MCC had a more porous structure,with a BET surface area of 2.04 times that of pristine biochar.Additionally,MCC had more carbonyl functional groups,and a higher capacity for phosphorus adsorption.When the initial phosphorus concentration was 40 mg/L, the phosphorous adsorption by MCC reached 16.59 mg/g.In simulated adsorption,the ideal adsorption conditions were found to be at pH 6 and 25 °C.When the initial phosphorus concentration is between 0 and 60 mg/L,the adsorption capacity of MCC increases with the increase in phosphorus content.The adsorption process followed the pseudo-secondary kinetic model and the Langmuir and Freundlich models,with both single molecular layer chemical adsorption and multi molecular layer physical adsorption.The theoretical saturation adsorption capacity of 32.60 mg/g demonstrated the potential for phosphorus removal from wastewater.
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    Low Frequency Wideband Sound Absorber Based on Extended-Neck Helmholtz Resonance
    XIAO Yafeng, YU Yuchi, WANG Jiahao, XU Feng, SHEN Danheng, LIU Yaoguang, LIN Yuanyan, KONG Peng, DENG Ke
    Journal of Jishou University(Natural Sciences Edition)    2025, 46 (1): 45-50.   DOI: 10.13438/j.cnki.jdzk.2025.01.007
    Abstract246)      PDF(pc) (1585KB)(141)       Save
    In order to solve the problem of low frequency sound absorption of Helmholtz resonator,an efficient wideband sound absorber with deep subwavelength thickness was designed by combining arrayed extended neck with Helmholtz resonance structure.The results show that the thickness of the absorber is only 1/36 of the wavelength corresponding to the absorption peak frequency,showing the sound absorption characteristics of deep subwavelength.When the resonant frequency is 315 Hz,the absorption peak amplitude of the sound absorber is as high as 0.985,which almost realizes the perfect absorption of sound energy.The sound absorption mechanism of the sound absorber is mainly due to the friction loss of sound energy in the inner wall of multiple extended necks.The arrayed extended neck provides additional tunability for the acoustic impedance of the absorber,and the operating frequency and bandwidth can be flexibly tuned in a wide band.Among the structural parameters,both the extended neck aperture and the extended neck tube length significantly affect the sound absorption performance of the sound absorber.The sound absorber has simple structure,thin thickness and good low frequency sound absorption performance.
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    Thoughts on Grade Classification of Agricultural Products
    PENG Shuting
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 77-81.   DOI: 10.13438/j.cnki.jdzk.2024.05.010
    Abstract244)      PDF(pc) (404KB)(103)       Save
    This paper provides a brief overview of the current situation and existing problems of grade classification of agricultural products in China from the perspectives of grade classification standards,technologies,and equipment.It deeply explores the importance of grade classification of agricultural products quality and puts forward some improvement measures according to practical work in China.The improvement measures include establishing a standard system,constructing a platform,upgrading intelligent equipment,and strengthening the construction of professional talent team for quality evaluation.
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    Impact of Policy Perception on College Students' Grassroots Employment Intention:A Moderated Mediation Model
    PENG Liping
    Journal of Jishou University(Natural Sciences Edition)    2025, 46 (1): 90-95.   DOI: 10.13438/j.cnki.jdzk.2025.01.014
    Abstract244)      PDF(pc) (625KB)(123)       Save
    To investigate the impact of policy perception on college students' grassroots employment intention,a mediating model was constructed in which policy perception impact s college students' grassroots employment intention through public service motivation,and the moderating role of career adaptability in this model was examined.Using structural equation modeling on 1 320 valid questionnaires,the results showed that:policy perception had a significant positively predictive effect on college students' grassroots employment intention.Public service motivation played a mediating role between policy perception and college students' grassroots employment intention.Career adaptability moderated both the direct effect of policy perception on college students' grassroots employment intention and the indirect effect through public service motivation.
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    Establishment and Preliminary Application of Tail Suspension Analysis System Based on DeepLabCut
    LI Zhihong, SHENG Yihua, GU Xinli, ZHOU Cenfei, WANG Huizhi, JIA Zhujun, ZHANG Jianzhi, LI Sidi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 84-91.   DOI: 10.13438/j.cnki.jdzk.2024.06.013
    Abstract243)      PDF(pc) (1486KB)(155)       Save
    A tail suspension analysis system has been established based on DeepLabCut (DLC) algorithm for evaluating depressive behavior in mice.Based on the DLC algorithm in deep learning technology,multi-path,semi-closed tail suspension hardware,the systems of software and hardware were constructed;this system and open field analysis system were applied to evaluate the tail suspension and open field behavioral changes in mice with reserpine depression model,intermittent alcohol consumption injury model,and periodontal silk ligation model.This system realized the synchronous analysis of head movement and limb movement in tail suspension,and automatically quantified 50 tail suspension indexes of dynamic and static type,posture type,and intensity type.It was found that in the reserpine depression model,compared with the control group,the movement distance,wall climbing times,and head swing times were reduced in the low-,medium-,and high-dose reserpine groups in 2 days,and the head swing times were reduced in the medium- and high-dose reserpine groups in 3 days and 4 days.In the intermittent alcohol consumption injury model,compared with the control group,the immobility time was reduced,the limb struggling times,movement distance,and movement time were increased in the low- and medium-dose ethanol groups,and the forelimb,hindlimb,and absolute struggling times were reduced in the high-dose ethanol group.In the periodontal silk ligation model,the movement distance and length,limb and absolute struggling times,and the total value of forelimb,hindlimb,and limb angles were reduced in the ligation group.Clearly,the DLC algorithm-based mouse tail suspension analysis system can accurately distinguish the behavioral characteristics of different mechanistic depression models.
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    Solving the One-and-Two Dimensional STO Equations Based on the PINN Method
    WANG Jing, DAI Houping, DONG Yaru
    Journal of Jishou University(Natural Sciences Edition)    2025, 46 (1): 18-24.   DOI: 10.13438/j.cnki.jdzk.2025.01.003
    Abstract241)      PDF(pc) (2914KB)(128)       Save
    Physically informed neural networks (PINN) model are used to solve the one-and two-dimensional Sharam-Tasso-Olver equations.
    The macroscopic equations and their initial margin conditions are used as physical information and transformed into the form of residuals,which are then used to construct a loss function to incorporate into the training process of the PINN model,and the Adam optimisation algorithm is used to achieve a high-precision solution.The numerical example results show that the loss function has high accuracy under a certain number of iterations,which verifies the reliability of the PINN model.
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    Non-Interference Identification Method of IoT Terminals Based on One-Dimensional Convolution Neural Network
    YANG Meng
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 26-31.   DOI: 10.13438/j.cnki.jdzk.2024.04.005
    Abstract240)      PDF(pc) (655KB)(204)       Save
    In view of the problem that IoT terminals are vulnerable to interference in the identification process,a non-interference identification method of IoT terminals based on one-dimensional convolution neural network is proposed.Acceleration data for different gaits are collected through the built-in acceleration sensor of the Internet of Things terminal and preprocessed through smoothing and windowing processing.Gait data fusion model is used to analyze user data under different behavior-position combinations,and random forest model is used to predict the position of IoT terminals and target data behavior.Behavioral target data are integrated with positional data to obtain gait fusion data.On this basis,a one-dimensional convolutional neural network model is constructed,which takes the fused data as input and outputs the user's identity recognition results after iterative training.The experimental results show that the non-interference identity recognition method for IoT terminals based on one-dimensional convolutional neural networks can accurately identify the identity of IoT terminal users in appropriate model parameter conditions.
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    Mechanism of Caulis Sinomenii in Treating Rheumatoid Arthritis Based on Network Pharmacology and Molecular Docking
    WU Ziqi, GONG Bufan, WANG Jianchao, PENG Huayong
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 44-53.   DOI: 10.13438/j.cnki.jdzk.2024.06.007
    Abstract238)      PDF(pc) (19913KB)(103)       Save
    To study the mechanism of Caulis Sinomenii in the treatment of rheumatoid arthritis,network pharmacology and molecular docking were used to screen 6 main active ingredients of Caulis Sinomenii from the TCMSP database.268 drug targets corresponding to the active ingredients were obtained through the PubChem library and Swiss Target Prediction.Subsequently,5 706 targets for rheumatoid arthritis were obtained through GeneCards,DisGeNET,and OMIM databases.By utilizing the Venny 2.1.0 platform to draw Venn diagrams,178 intersection targets between the active ingredients of Caulis Sinomenii and rheumatoid arthritis diseases were identified.A network diagram illustrating the interaction between the active ingredients of Caulis Sinomenii and rheumatoid arthritis disease was constructed using Cytoscape 3.10.0.Additionally,a drug component target protein network diagram was created.GO enrichment analysis and KEGG pathway enrichment analysis were conducted using the DAVID database.Molecular docking simulation was performed between the target and the active ingredients of the drug using Autodock software.The results revealed that NR3C1,AKT1,SRC,PPARG,and JUN are the key target proteins for the anti-rheumatoid arthritis effect of Caulis Sinomenii.The GO enrichment analysis results indicated that biological processes mainly include G protein-coupled receptor signaling pathway,coupled to cyclic nucleotide second messenger G,vascular process in circulatory system,adenylate cyclase-modulating G protein-coupled receptor,peptidyl-serine phosphorylation,etc.The cellular components mainly include integral component of presynaptic membrane,intrinsic component of presynaptic membrane,membrane raft,membrane microdomain,etc.The molecular functions mainly involve nuclear receptor activity,ligand-activated transcription factor activity,catecholamine binding,protein tyrosine kinase activity,etc.According to the KEGG enriched bubble diagram,it can be inferred that the affected pathways include the cancer pathway,the neuroactive ligand receptor interaction pathway,and the inflammatory mediator regulatory pathway of the TRP channel.The molecular docking results indicated that the active ingredients,including β-sitosterol,razmanine,xylosterol,sinomenine,and levodontidine,are associated with the core targets NR3C1,AKT1,SRC,PPARG,and JUN,all showing good binding activity.The treatment of rheumatoid arthritis with Caulis Sinomenii may involve a multi-component,multi-target,and multi-pathway process,which includes regulating inflammatory cytokines,immune cells,cell cycles (such as apoptosis and burning),and osteoblasts and osteoclasts to treat rheumatoid arthritis.
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    Optimization of Extraction Process and Vitro Antioxidant Activity of Total Polysaccharides from Polygonatum odoratum
    ZHANG Yan, ZHANG Yang, CHEN Jiarui, YAO Shufeng, CHENG Jiang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 37-43.   DOI: 10.13438/j.cnki.jdzk.2024.06.006
    Abstract237)      PDF(pc) (6072KB)(102)       Save
    The extraction process and antioxidant activity of total polysaccharide from the rhizome of Polygonatum odoratum were evaluated.The total polysaccharide was isolated from Polygonatum odoratum rhizome through ultrasound-assisted water bath heating extraction method.The influences of material-liquid ratio,ultrasonic power,ultrasonic extraction temperature on the extraction rate of the total polysaccharide were investigated.Based on the results of single-factor experiments,the response surface experiments give the optimal extraction conditions of total polysaccharide from the rhizome of Polygonatum odoratum∶ material-liquid ratio 1∶15 (g∶mL),ultrasonic power 300 W,extraction time 60 min,and ultrasonic extraction temperature 60 ℃.Under these extraction conditions,the total polysaccharide yield of Polygonatum odoratum was 13.58%.The results of the antioxidant activity test showed that when the mass concentration of Polygonatum odoratum polysaccharide was 2.75 g/L,the scavenging rates of Polygonatum odoratum polysaccharide on DPPH radicals and OH radicals were 34.18% and 62.04%,respectively.
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    Determination of Levofloxacin on Carboxylated Multi-Wall Carbon Nanotubes Modified Glassy Carbon Electrode
    WANG Ying, MA Dongyun, SHEN Jinghui, JING Wenhui, ZHAO Liman, YUAN Huan, LI Bingyin
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 76-81.   DOI: 10.13438/j.cnki.jdzk.2024.04.011
    Abstract236)      PDF(pc) (911KB)(248)       Save
    Electrochemical behavior of levofloxacin on carboxylated multi-walled carbon nanotubes(c-MWCNTs) modified glassy carbon electrode (c-MWCNTs/GCE) was studied,and the content of levofloxacin was determinated.The results showed that the electrode had good electrocatalysis to levofloxacin.In a mixed phosphate (NaH2PO4-Na2HPO4) buffer solution with pH 5.0,the excellent linear relationship was kept between oxidation peak currents and the concentration of levofloxacin in the range of 1×10-5~4×10-4 mol/L with the correlation coefficient of 0.998,and the detection limit of 2.87×10-6 mol/L.Under the optimal test conditions,the recoveries of levofloxacin tablets were 98.7%~103.0%,and the relative standard deviation values of determination results were 1.31%~3.99%(n=5).Thus the c-MWCNTs/GCE has good electrochemical response to levofloxacin with high sensitivity and can be used for determination of levofloxacin content in drugs.
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    Application of Complex Analysis Theory to Calculate a Class of Fresnel Type Integral
    JIANG Yi, SU Lingyan
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 9-12.   DOI: 10.13438/j.cnki.jdzk.2024.03.002
    Abstract235)      PDF(pc) (310KB)(182)       Save
    For the Fresnel-type integral which is difficult to be solved by real function theory,the Dirichlet test is first applied to prove its convergence.Then,the general convergence result of Fresnel-type integral with xn-2 or xm are given by applying the circulatory integral method and Cauchy integral theorem.
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    Synthesis,Characterization and Luminescence of Eu(Ibu)3phen
    WANG Ying, SHEN Jinghui, HU Lina, MA Dongyun, SHI Chengyang, LI Bingyin
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 88-90.   DOI: 10.13438/j.cnki.jdzk.2024.03.012
    Abstract234)      PDF(pc) (442KB)(142)       Save
    Eu (Ibu) 3phen was synthesized,with  non-steroidal anti-inflammatory drug Ibuprofen as the first ligand,Phenanthroline as the second ligand and the rare earth ion Eu3+ as the central ion by solvent method.The structure of the complex was characterized by elemental analysis,UV spectroscopy,and infrared spectroscopy,and the fluorescence properties of the complex were studied.The results indicate that ibuprofen can effectively serve as an antenna ligand,greatly sensitize luminescence of Eu3+,so the fluorescence emission spectra of the complex Eu (Ibu) 3phen exhibit strong characteristic fluorescence emission peaks of europium ions at 589 nm and 612 nm.The complex has good luminescence performance,so it can be used as a kind of environmentally friendly fluorescent material.
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    Effect of Ginger Starch on the Characteristics of Ginger Powder
    XIONG Kun, SHUAI Jingjing
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 45-54.   DOI: 10.13438/j.cnki.jdzk.2024.03.007
    Abstract229)      PDF(pc) (948KB)(417)       Save
    With fresh ginger as raw material,the original ginger juice,precipitation and supernatant were separated after juicing,and freeze-dried ginger powder 1,2,3 were obtained respectively,and then their dispersibility,solubility,sensory characteristics,volatile components were measured.The results showed that the starch retention rates of three kinds of ginger powder were ginger powder 2,ginger powder 1 and ginger powder 3 in descending order.The color of ginger powder 2 was the brightest and L* was the largest,but the solubility of ginger powder 3 was significantly better than the other two.The sensory comprehensive evaluation showed no significant differences in  ginger powder 3 and ginger powder 1,but better sensory scores than that of ginger powder 2.A total of 103 volatile components were identified,including 54 olefins,20 alcohols,11 aldehydes,7 ketones and 11 esters.Olefins,alcohols and ketones were the main volatile components in ginger powder,and their relative contents were 67.33%,14.67% and 13.67%,respectively.20 volatile components with VIP higher than 1 had the greatest effect on the flavor of the three ginger powder.Cluster analysis showed that the three kinds of ginger powder could be clustered into categories I and Ⅱ.Ginger powder 1 and ginger powder 3 had similar flavors,so they were classified as class I.The two euclidean distance was 0.342 0,the euclidean distance difference between class Ⅱ and class I was only 0.011 0,indicating that the difference between class II and class I was  not significant.
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    Evaluation on the Integration Effect of Intangible Heritage and Tourism in Traditional Villages in Western Hunan
    YANG Yixian, LIU Zheng, LIU Shuiliang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 82-88.   DOI: 10.13438/j.cnki.jdzk.2024.05.011
    Abstract229)      PDF(pc) (421KB)(134)       Save
    Based on the theories of industry integration and stakeholders,this paper constructs an evaluation index system of the integration effect of intangible cultural heritage and tourism in traditional villages from four aspects of economy,culture,society and ecology,and makes an empirical analysis by taking four typical national-level traditional villages (Zhushan Village,Shiyanping Village,Shibadong Village and Huangdu Village) in western Hunan as examples.The results show that the economic,social and ecological effects of Huangdu Village are good,the cultural effects are good,and the coordination among the effects is high.The ecological and social effects of Zhushan village are good,and the economic and cultural effects are good.The ecological effect of Shibadong Village is very good,and the economic,cultural and social effect is good.The economic effect of Shiyanping village is low,the cultural effect is ordinary,the ecological and social effect is good,and the coordination among the effects needs to be enhanced.In order to further enhance the integration effect of intangible cultural heritage and tourism in traditional villages in western Hunan,and realize the deep and high-quality integration of the two,countermeasures are proposed from five stakeholder levels:government,community,villagers,enterprises and tourists.
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    The Second Order Adaptive Moving Mesh Method for a Singularly Perturbed Fredholm Integro-Differential Equation
    LUO Dan, MAO Zhi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 15-25.   DOI: 10.13438/j.cnki.jdzk.2024.04.004
    Abstract225)      PDF(pc) (1276KB)(232)       Save
    An exponentially fitted finite difference scheme constructed by the base function method and the compound trapezoidal formula is applied to make discrete a class of singularly perturbed Fredholm integral differential equation.Combining the truncation error estimate,the boundary estimate and the stability analysis,the second order uniform convergence in the infinity norm with respect to the perturbation parameter for the adaptive moving mesh method is proved.Based on the above theoretical analysis,the algorithm to produce the mesh is designed.
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    Investigation and Analysis of Threatened Plants in Baojing County
    JIANG Long, CHEN Dahua, JIANG Mei, ZHANG Daigui
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 59-66.   DOI: 10.13438/j.cnki.jdzk.2024.04.009
    Abstract222)      PDF(pc) (481KB)(274)       Save
    To grasp the current situation of threatened plants in Baojing County,methods such as field investigation,specimen collection and organization,and literature review were adopted to investigate and analyze the threatened plants of the area.The results show that there were 70 species of threatened plants in 36 families,55 genera,of which 4 were critically endangered,21 were endangered,and 45 were vulnerable.Among the categories,angiosperms were the most threatened.In the composition of family and genus,the threatened plants mainly belong to single species and single species.In the composition of life forms,the threatened plants were mainly herbaceous plants.The floristic composition of threatened plant genera is complex,their origin and development are closely related to tropical distribution,and East Asian components are prominent,showing subtropical characteristics.The population of threatened plants is normally distributed,and the geographical distribution is unbalanced.Habitat degradation or loss and direct harvesting and felling are the main risk factors for threatened plants.Three protected areas in Baojing County provide effective protection for threatened plants.
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    Impact Resistance Performance Assessment of Bridge Piers in Navigable Holes Under the Action of Ship Impact
    LI Yue, YAN Yong, NING Zhe, SHAN Honglan, LUO Anran
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 19-28.   DOI: 10.13438/j.cnki.jdzk.2024.03.004
    Abstract221)      PDF(pc) (1690KB)(328)       Save
    Considering the complex navigational environment of waterways spanned by bridges,which are prone to ship-bridge collision accidents,this study evaluates the impact resistance performance of navigational pier columns of a certain cross-river cable-stayed bridge project under the action of ship impacts.The LS-DYNA simulation software is used to model the process of ship impacting on the pier,obtaining the impact force of the ship.Subsequently,the mechanical response of the pier under a combination of loads including ship impact,self-weight,and buoyancy is calculated,and these responses are compared with the mechanical indicators of the pier in a critical failure state to assess the pier's resistance performance.The evaluation successfully determines the resistance performance of the pier.The study's findings indicate that the bending and shear resistance checks for piers 28# and 30# do not meet the requirements,necessitating reinforcement and the installation of collision protection facilities.
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    Ecological Security Assessment of Lishui River Basin in Zhangjiajie City
    CHEN Dongsu, YANG Yi, YAN Li, LI Qiaoyuan
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 63-70.   DOI: 10.13438/j.cnki.jdzk.2024.03.009
    Abstract220)      PDF(pc) (649KB)(209)       Save
    Taking Lishui River basin in Zhangjiajie city as the research object,through fieldwork,collecting historical data and on-site monitoring,combining with the domestic and foreign ecological security assessment theory,using the "pressure-state-function-risk-response" (PSFRR) model,the ecological security assessment index system of Zhangjiajie Lishui River basin was constructed (5 factor layers,20 scheme layers and 43 index layers) to evaluate the ecological security index of the river basin.The results showed that the ecological security index of Zhangjiajie Lishui River basin was at a good level,and the ecological damage was controllable.Affected by human activities and agricultural development along the river,the habitat of the river basin was damaged,the integrity index of aquatic organisms was low,the water conservation capacity was insufficient,and the stability of the river basin ecosystem was threatened.In view of the problems mentioned and the requirements of river basin ecological protection,the corresponding measures and countermeasures were put forward from the aspects of river basin water ecological environment governance,ecosystem protection and restoration,ecological security management and the construction of river basin ecological environment protection system.
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    Hotel Pricing Decision in Online Travel Agent Auction Sales Through Dual Channels
    XU Lei, CAI Jiangang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (3): 82-87.   DOI: 10.13438/j.cnki.jdzk.2024.03.011
    Abstract217)      PDF(pc) (3883KB)(140)       Save
    In the tourism supply chain system composed of hotel and online travel agent (OTA),for OTA  hotel room auction sales,a centralized decision-making model for the hotel and the OTA and a decentralized decision-making model with hotel as the leading and OTA as the follower were constructed,and the optimal decision-making for the hotel and the OTA was given by Backward induction analysis.The results of the study show that the number of hotel rooms sold by the OTA is affected by both price and commission.The increase of sales price and commission will increase the number of the OTA aution.The optimal commission and the optimal auction quantity will  increase with the number of OTA users and the auction duration.Compared with decentralized decision-making,centralized decision-making tourism supply chain system has greater room auction quantity and higher sales price.On this basis,the hotel and the OTA should cooperate with the concept of community of interest to maximize the overall benefits and promote the high-quality development of both sides.
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    Influence of c-Normality on p-Solvability of Finite Groups
    JIA Lei, LUO Xiaoliang
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (4): 11-14.   DOI: 10.13438/j.cnki.jdzk.2024.04.003
    Abstract216)      PDF(pc) (273KB)(241)       Save
    The necessary and sufficient condition for finite groups to be p-nilpotent groups is given by using c-normality,and two sufficient conditions for finite groups G to be p-supersolvable groups are obtained by investigating the c-normality of Sylow subgroups and their maximal subgroups.
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    Afforestation Effect and Stand Structure of 36-Year-Old Liriodendron chinense and Sassafras tzumu Mixed Forest
    XIANG Ming, LIU Congquan, PENG Mengyou, YAO Maohua, XIANG Zuheng, MA Fengfeng, HE Yong, ZHANG Peng, LIU Dongmei
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 68-76.   DOI: 10.13438/j.cnki.jdzk.2024.05.009
    Abstract213)      PDF(pc) (890KB)(169)       Save
    The 36-year old mixed forest of Liriodendron chinense and Sassafras tzumu in the middle altitude mountain area of Longshan County was studied from the aspects of the mixing effect of the mixed forest,the influence of spinning tillering on the growth of Liriodendron chinense and the stand structure.The results showed that Liriodendron chinense and Sassafras tzumu were not suitable for the construction of mixed forest.The 36-year old mixed forest had medium stand growth,and the existing density was 756±80 trees/hm,which could be used for medium and large-diameter wood cultivation.Tillering has a significant effect on the diameter,crown width and stock of Liriodendron chinense.The diameter distribution of Liriodendron chinense showed a left-leaning approximate normal distribution,and the model applicability χ test only followed the normal distribution,but not the Weibull distribution.The height distribution of Liriodendron chinense showed a right-leaning approximate normal distribution,and its model applicability did not pass the χ test and did not conform to the normal distribution or Weibull distribution.The cubic equation is the best fitting curve equation for the height and diameter of liriodendron tree.
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    Purification Process of Total Flavonoids from Lilium lancifolium Thunb and Its Antibacterial Activity
    ZHU Lanping, YUAN Jiao, YUAN Jieying, YIN Xinlian, LIU Ying, CHENG Jiang, YAO Shufeng
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 24-30.   DOI: 10.13438/j.cnki.jdzk.2024.06.004
    Abstract210)      PDF(pc) (915KB)(136)       Save
    Through comparing the static adsorption-desorption performance of 7 kinds of macroporous resins,the best macroporous resin with high adsorption rate and desorption rate was selected.The optimal purification process of Lilium lancifolium by macroporous resin was selected by single factor experiment and orthogonal experiment,and the total flavonoid content and antibacterial activity before and after purification were determined.The results showed that the macroporous resin with high adsorption and desorption performance was AB-8.The optimal purification process was as follows:the total flavonoid concentration of the feed solution was 0.076 4 g/L,the pH value was 4,the adsorption time was 8 hours,the solvent volume fraction was 60%,the solvent volume was 120 mL,and the desorption time was 10 hours.The total flavonoid content after purification was 11.55%,which was 5.3 times that of the purification before.The inhibition zone diameter of the purified total flavonoid was larger than that of the total flavonoid before purification,and the inhibitory effect on Staphylococcus aureus was higher than that on Escherichia coli.
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    Research Status and Clinical Application of the Tujia Medicinal Swertia davidii
    HE Tingxiang, FU Qingqing, ZHU Jiaxin, PENG Shengwen, LIU Fen
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (6): 1-10.   DOI: 10.13438/j.cnki.jdzk.2024.06.001
    Abstract209)      PDF(pc) (1773KB)(122)       Save
    To further explore the medicinal potential of Tujia medicine,this paper comprehensively reviews the research progress of Swertia davidii in six aspects,including crude drug identification,chemical composition,content determination,extraction technology,pharmacological action,and clinical application,by referring to Chinese herbal medicine classics and related literature.The results indicate that Swertia davidii is abundant in various chemical components,including xanthones,iridoids,triterpenoids,and flavonoids,and exhibits diverse pharmacological activities such as anti-inflammatory,antibacterial,antitumor,antiviral,and antioxidant properties.In clinical practice,Swertia davidii is extensively used in the treatment of pulmonary fever,pneumonia,jaundice,cholecystitis,acute and chronic enteritis,gynecological inflammation,dysentery,diarrhea,urinary tract infections,scabies,oral ulcers,and other diseases,demonstrating significant medicinal value.
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    Traditional Chinese Medicine Management of Excessive Stomach Heat Type Periodontitis:A Clinical Research Review
    HU Caihua, LI Chao, CHANG Chen, GONG Lingziyun, OU Zhongmin, LI Qican, ZHANG Luoqin
    Journal of Jishou University(Natural Sciences Edition)    2025, 46 (1): 78-84.   DOI: 10.13438/j.cnki.jdzk.2025.01.012
    Abstract208)      PDF(pc) (765KB)(188)       Save
    By reviewing and screening the literature on the treatment of periodontitis with excessive stomach fire in Chinese medicine from 1995 to 2024,which was included in databases such as CNKI,Wanfang,and VIP,this paper summarizes the research progress of Chinese medicine in the treatment of this disease.The results show that periodontitis falls within the category of "tooth socket wind and tooth bleeding" in Chinese medicine.The most common clinical syndrome is excessive stomach fire,which is caused by accumulated heat in the stomach ascending along the meridians.The treatment principle is to clear stomach heat and purge fire,cool blood and detoxify.The clinical treatment methods of periodontitis with excessive stomach fire in Chinese medicine are diverse,including traditional Chinese herbal medicine,acupuncture,auricular point plaster,and gargling.The main treatment method in clinical practice is traditional Chinese medicine,with frequently used herbs including coptis,rehmannia,paeonia,cimicifuga,and angelica.The therapeutic mechanism mainly involves reducing the levels of pro-inflammatory cytokines,reducing oxidative stress responses,inhibiting the growth of periodontal pathogenic bacteria,and enhancing the activity of periodontal ligament stem cells.The treatment of this disease with Chinese medicine is effective,safe,has few side effects,and is well accepted by patients.
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    Characteristics and Function of the Urine Microbiome from Prostatic Hyperplasia Patients
    PENG Qiaomu, FAN Shiqiu, TIAN Jingjing, XIANG Tao, LI Hui, QU Xinyi
    Journal of Jishou University(Natural Sciences Edition)    2024, 45 (5): 52-60.   DOI: 10.13438/j.cnki.jdzk.2024.05.007
    Abstract204)      PDF(pc) (2815KB)(94)       Save
    This work is to analyze the community structure and species abundance of urine microbiome,as well as the differential microflora in three groups of healthy people,preoperative and postoperative prostatic hyperplasia patients,and to unearth the mechanism of the differential microflora related to the development of prostatic hyperplasia.Urine samples from healthy people (control group,C),preoperative (patient group,B) and postoperative (postoperative group,S) patients with prostatic hyperplasia were collected,and sequenced by whole metagenome shotgun sequencing.Bioinformatics analysis was carried out by related software.The results were as follows:the microbial diversity of B group samples (preoperative BPH patients) was lower than that of C and S groups of samples.At the phylum level,the abundance of Firmicutes,Actinobacteria and Bacteroidetes between C and S groups had no difference,but was significantly higher than that of B group.At the genus level,the abundance of Escherichia,Pseudomonas,Acinetobacter and Shigella between C and S groups had no difference,but was lower than that of B group;the abundance of Streptococcus and Prevotella in C and S groups of samples had no difference,but was higher than that of B group.Functional annotation at the PHI-base database showed that the abundance of some mutualistic factors in B group were significantly higher than that of C and S groups,such as reduced virulence factors,unaffected pathogenicity factors,increased virulence factors and lethal factor,then tended to return to the level of healthy people in S group.Functional annotation at the VFBD database showed that the abundance of some virulence factors in B group was significantly higher than that of both C and S groups,such as Type IV fimbria,capsule I,flagellum,Type III secretion system,colibactin,enterobactin,etc.,then tended to return to the level of healthy people in S group.In conclusion,decreased microbial diversity in the urinary tract microbiome and the increased or decreased abundance of the specific microbial taxa during the dysbiosis of urinary microflora might be positively correlated with prostatic hyperplasia of the patients.The increased abundance of some interaction factors and virulence factors of the differential microflora in the patient urine might induce the development of prostatic hyperplasia.
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