journal6 ›› 2000, Vol. 21 ›› Issue (1): 78-81.

• Scientific research bulletin • Previous Articles     Next Articles

Improve on Method of Separation and Synthesis of 4- Hydroxyphenyl- 21H, 23H- Porphine


  1. ( College of Life Science and Chemistry Jishou University, Jishou 416000, Hunan China)
  • Online:2000-03-15 Published:2013-01-16

Abstract: Method of separat ion of a hydroxyphenyl- 21H, 23H- porphine[ 5- ( 4- hydroxyphenyl) - 10, 15, 20-triphenyl- 21H, 23H- porphine( H2TPPOH) ] and many hydroxyphenyl- 21H, 23H- porphine[ 5, 10- di( 4- hydroxyphenyl) - 15, 20- diphenyl- 21H, 23H- porphine( H2TPP( OH) 2) ; 5- phenyl- 10, 15, 20- tri( 4- hydrox yphenyl) - 21H, 23H- porphine( H2TPP( OH) 3) ] was improved.The results showed that in the course of separating all kinds of hydroxyphenyl porphine, by the new method, the separate efficiency and product purity were better, the using amount of eluant was less and the column separation times was shorter. In addition, the influence of the ratio of reactants, drop speed of pyrrole solution and operational method on the yield of synthesing all kinds of hydroxyphenyl porphine were inves  tigated,wi th 3:1. 05:4( C6H4CHO: HOC6H4CHO:C4H5N, mole ratio) , drop pyrrole solution in 3 minutes and strong motor stir, the yield of the H2TPPOH was increased.

Key words: 4- hydroxyphenyl-21H, 23H-porphine, synthesis, separation

WeChat e-book chaoxing Mobile QQ