Journal of Jishou University(Natural Sciences Edition)

Differentiability for Measure Neutral Functional Differential Equation

TIAN Rui, LI Baolin

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 1-6.

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In the framework of the theory of generalized ordinary differential equations,by virtue of the one-to-one correspondence between measure neutral functional differential equations and generalized ordinary differential equations,sufficient conditions for differentiability of measure neutral functional differential equations are put forward.On the basis of defining a new operator Ψ(λ,y)(t),differentiability for measure neutral functional differential equations is proved.

Reachable Set Boundary Estimation for Neutral Markovian Jump Systems

ZHANG Xipan, SHEN Changchun

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 7-16.

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By constructing an appropriate Lyapunov functional and using the improved Wirtinger integral inequality combined with the free-weighting matrix idea and the time-delay segmentation method,we have obtained the boundary conditions for the small reachable set of a class of neutrual Markovian jump systems (NMJSs) with distributed delay in the form of linear matrix inequalities.

Reachable Set Estimation for Generalized Semi-Markov Jump Systems

PENG Chunyuan, SHEN Changchun

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 17-23.

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Based on Lyapunov functional method,the reachable set boundary estimation problem for a class of singular semi-Markovi jump systems with time-varying delays is studied.Firstly,the boundary of the fast and slow subsystem is obtained by the piecewise analysis method and integral inequality technique.Then,the upper and lower boundary of semi-Markov transfer rate is used to deal with the problem of abnormal transfer rate.Finally,the sufficient condition of the existence of the reachable set boundary of the system is given in the form of linear matrix inequality.

An Improved Whale Optimization Algorithm Based on Levy Flight and Brownian Motion

YU Cunwei, MO Liping, WAN Runze

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 24-32.

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A whale optimization algorithm based on Levy flight and Brownian motion is designed to overcome the disadvantages of whale optimization algorithm such as low accuracy,slow convergence and easiness to fall into local optimum.First,Levy flight method is used to initialize the whale population to increase the diversity of the initial population.Then,according to the principle of Brownian motion,the position update of the whale population is randomly perturbed to avoid the algorithm falling into local optimization in advance.The improved whale optimization algorithm is compared with whale optimization algorithm,particle swarm optimization algorithm,genetic algorithm and ant colony optimization algorithm on seven different benchmark test functions.The experimental results show that the improved whale optimization algorithm is superior to the other four algorithms in terms of solution accuracy and convergence speed.At the same time,simulation and comparison experiments are carried out on the initial solution exploration range of the improved whale optimization algorithm using Levy flight strategy and the whale optimization algorithm using random search strategy in the initialization stage.The experimental results show that the improved whale optimization algorithm can avoid falling into local optimization in a certain program.

A Novel MEHM Blind Spectrum Sensing Algorithm Based on Random Matrix Theory

LIU Tingting, LEI Kejun, TAN Zhewen, TIAN Chong, TIAN Xinxin, YANG Xi

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 33-38.

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A novel maximum eigenvalue-harmonic mean (NMEHM) blind spectrum sensing algorithm is proposed,using the results of the distribution of the limiting eigenvalues of the sample covariance matrix in random matrix theory.The proposed algorithm significantly improves the detection performance of the traditional MEHM algorithm and achieves better detection performance than the classical eigenvalues-based detection algorithms;at the same time,the proposed algorithm does not require a priori knowledge of the primary user signal and wireless channel,which can availably overcome the effect of noise uncertainty.Simulation results demonstrate the validity of the proposed algorithm.

Shock Absorption Effect of Shock Absorbing Layer Settings of Urban Utility Tunnel

CUI Guangyao, KE Xu, GUO Yanjun

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 39-46.

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To improve the seismic resistance behavior of the soft-stratum of urban utility tunnel in strong earthquake areas,this paper takes the utility tunnel as the research object and studies,the shock absorption effect of the shock absorbing layer with different settings through finite difference software FLACD.The results show that compared with the condition without seismic measures,the maximum settlement of the condition with the bedding shock absorbing layer decreases by 1.61%,the maximum and minimum principal stresses decrease by 29.75% and 4.88% respectively,the maximum shear stress decreases by 18.49% and the minimum safety factor increases by 15.13%;the maximum settlement of the condition with setting a semi-ring shock absorbing layer decreases by 1.55%,the maximum and minimum principal stresses decrease by 34.12% and 18.06% respectively,the maximum shear stress decreases by 31.86% and the minimum safety factor increases by 18.33%;the maximum settlement of setting a full-ring shock absorbing layer decreases by 16.92%,the maximum and minimum principal stresses decrease by 61.04% and 28.84% respectively,the maximum shear stress decreases by 35.78% and the minimum safety factor increases by 32.46%.It can be concluded that the shock absorption effect of setting a full-ring shock absorbing layer is better than the cushion layer and the semi-ring layer.

Antibacterial Activity and Identification of Endophytic Fungi YDZ-8 Isolated from Lavandula angustifolia Mill.

CHEN Tianyi, BAIDOULA·Nulan, TUERDEBIEKE·Mayila, ENTOMACKY·Borrathyba

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 47-51.

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The endophytic fungi were isolated from the roots of Lavandula angustifolia Mill. by surface disinfection method and tissue isolation method,and the antibacterial activity against the Staphylococcus aureus was evaluated by paper disk diffusion method.The active isolates were identified in terms of their morphological features by phylogenetic analysis based on ITS sequence of rDNA gene.The results showed that the endophytic fungi of YDZ-8 had remarkable antibacterial activity against Staphylococcus aureus strain CGMCC1.872.Fungal morphological and molecular identification demonstrated that the endophytic fungi strain YDZ-8 represented Trichoderma harzianum.

Effect of Diammonium Glycyrrhizinate on Apoptosis in Rats with Ulcerative Colitis

SHENG Yihua, ZHOU Minggao, FAN Taiping, TAN Xiaowen, ZENG Xingyao, LI Ping, LI Sidi

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 52-57.

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To explore the effect of diammonium glycyrrhizinate on apoptosis of peripheral blood inflammatory cells in rats with ulcerative colitis.UC model was induced by TNBS and ethanol,both with colonic mucosa tissue,which were assigned into four groups,namely control group,model group,western medicine group (administrated by sulfasalazine enteric-coated tablets),and licorice group (administrated by diammonium glycyrrhizinate).Pathomorphological changes of colon tissue were dynamically observed in the 0,2^nd,and 4^th week after model establishment,and the apoptosis rates of LPL and PMN in the blood were dynamically observed by flow cytometry in the 2^nd and 4^th week respectively.Compared with the control group,pathological changes in colon tissue were showed in model group by HE staining,and the colon wet weight and the colon weight index increased.Compared with the model group,the pathological changes of colon tissue in DG group and western medicine group were recovered in a certain degree in the 2^nd and 4^th week.The colon wet weight and colon weight index decreased significantly in DG group in the 4^th week.Apoptosis of LPL and PMN in blood of UC model was delayed in the 2^nd week after model established,while DG and western medicine promoted poptosis of LPL and PMN.In the 4th week,apoptosis rate of LPL in UC model still decreased,but apoptosis rate of LPL in DG and western medicine group was higher than that of model group.It can be concluded that DG and sulfasalazine enteric coated tablets can still improve the apoptosis rate of LPL.Occurrence and development of ulcerative colitis is related with apoptosis reduction of LPL and PMN to some degree.DG can relieve UC through regulating apoptosis rate of LPL and PMN in blood.

Effect of Plant Rodenticides on the Reproduction Performance of Female Microtus fortis

YANG Dongmei, ZENG Sichun, TAO Shuanglun, LI Anna, LI Jiacheng, HE Qian, LI Shuang, LI Junnian

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 58-63.

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To measure the effects of plant rodenticide on reproductive performance of Microtus fortis,the effects of plant rodenticide on serum estrogen,reproductive organ index，litter size and reproductive delay of Microtus fortis were studied by one-time gavage in laboratory.The results showed that different doses of plant rodenticide significantly increased the uterine index and changed the uterine morphology of M. fortis,but did not affect the level of serum estradiol and uterine length.The serum follicle-stimulating hormone (FSH) content and ovarian index of female voles gavaged 50 mg/kg rodenticide were significantly increased.It is showed that different doses of plant rodenticide could delay the time of first reproduction and litter size of female M. fortis,and the recovery time of reproduction in female M. fortis gavaged 10 mg/kg,25 mg/kg and 50 mg/kg groups was 11 d,22 d and 48 d longer than that of the control group,respectively.

Anti-COVID-19 Pandemic Effect of Plant Flavonoids: Use of Green Tea Flavonoids

Deyu Xie, Seyit Yuzuak, Yue Zhu, Qingzhong Peng

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 64-86.

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In 2020,we reported that flavan-3-ol gallates (F3Gs),dimeric proanthocyanidins (PAs),and F3Gs and PA-rich extracts of green tea inhibited the activity of the main protease of SARS-CoV-2.Recently,we reported that F3Gs and other flavonoids inhibited the replication of human coronavirus 229E in human cells.In addition,a large number of articles reported the beneficial effects of green tea and flavonoids on the therapy of COVID-19.Since December 2020,we have continued to use demographic and ethno-pharmaceutical approaches to investigate the use of green tea during the recovery of COVID-19 volunteers in USA and Turkey.We collected data from more than 23 people who used green tea during their recovery at home in USA and five consented to report their recovery experience.We collected detailed recovery information from 100 volunteers (from 20-month to 96 years old) in Turkey,who only used green tea for their recovery without any medical assistance.A pearson correlation coefficient (PCC) analysis indicated a negative correlation between the recovery days and the daily green tea cups consumed by those Turkish volunteers.The more cups of tea they drank,the fewer days they needed for their recovery.Furthermore,the data of the annual per capita tea consumption (PCTC) were obtained from 208 and 100 countries in 2020 and 2021,respectively.Turkey had the highest PCTC values,3.0 and 3.4 kg in 2020 and 2021 and their COVID-19 death rates were lower than 1%.People in many countries of Latin America did not drink tea,while the death rates were relatively high.For example,Mexico had the highest death rate in 2020,about 11%.Furthermore,the average death rates of COVID-19 were calculated for 115 and 121 countries in 2020 and 93 countries in 2021.PCC analysis indicated a promising negative association between PCTC and death rates in these countries.The more tea infusions were consumed,the lower the death rates of COVID-19 occurred.These data indicate that the valuable benefit of tea especially green tea to help the recovery from COVID-19 and reduce death (All data were approved for publication by the institutional review board (IRB),the Ethic Commission for Un-Interventional Clinical Studies,and volunteers).

Diversity of Wild Medicinal Plant Resources and Correlation Analysis of Medicinal Material Properties in Dehang Scenic Spot of Hunan Province,China

TAN Lu, XIANG Xiaomei, LIU Bing, WANG Zhicheng, CHEN Gongxi

Journal of Jishou University(Natural Sciences Edition), 2023, 44(2): 87-95.

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Correlation between medicinal material properties and diversity of wild medicinal plant resources in Dehang scenic spot was analyzed.The species composition,the life forms,the geographical distribution and the medicinal parts were statistically analyzed by field investigation,specimen arrangement and literature review.On this basis,association rule method was used to analyze the correlation between medicinal plant family and genus,medicinal chemical composition and medicinal efficacy.The results show that there are 617 species of wild medicinal plants belonging to 406 genera and 137 families in Dehang scenic spot.The life forms are mainly herb.As for the floristic geographical distribution at the family level,the medicinal plant flora is mainly global and pan-tropical;at the genus level,the medicinal plant flora is mainly north temperate and pan-tropical;and at the species level,the medicinal plant flora is mainly East Asia.The medicinal parts are mainly the whole plant,roots and rhizomes.A total of 36 strong association rules were screened by association rule analysis,among which liliaceae-saponins,zanthoxylum-alkaloids are highly correlated in terms of chemical components,and Liliaceae-expectorant cough suppressant and anti-asthmatic drug,and Hypericum-styptic are highly correlated in terms of medicinal efficacy.The results show that species of the medicinal plants are rich in Dehang scenic spot and their life forms are diverse.The floristic geographical composition is complex.According to the correlation between medicinal plant family,chemical composition and efficacy,it can be concluded that new drugs with better efficacy and less toxicity can be found in nature.

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