Abstract: In the framework of the theory of generalized ordinary differential equations,by virtue of the one-to-one correspondence between measure neutral functional differential equations and generalized ordinary differential equations,sufficient conditions for differentiability of measure neutral functional differential equations are put forward.On the basis of defining a new operator Ψ(λ,y)(t),differentiability for measure neutral functional differential equations is proved.

Key words: measure neutral functional differential equations, generalized ordinary differential equations, differentiability, Lebesgue-Stieltjes integral