journal6 ›› 2009, Vol. 30 ›› Issue (5): 87-92.

• Biological resources • Previous Articles     Next Articles

Metabolic Dynamic of Camptothecin and 10-Hydroxycamptothecin in  Camptotheca acuminata Decne Leaves During the Process of Growth


  1. (1.Light Industry and Chemical Enginnering Research Institute,South China University of Technology,Guangzhou 510640,China;2.The Biology Research Institute,Guizhou Academy of Science,Guiyang  550009,China)
  • Online:2009-09-25 Published:2012-04-21
  • About author:LI Xiang-li (1980-),female,born in Henan Province,Ph. D.,mainly researches on food chemical engineering
  • Supported by:

    Supported by Sino-French Advanced Research Project (PRA B02-07);Scientific and technological achievements promotion project of Guangzhou city (2006C13G0011)

Abstract: An HPLC method for the simultaneous determination of CPT and HCPT in Camptotheca acuminata Decne.leaves was established.Using this assay,CPT and HCPT in leaves of Camptotheca acuminata Decne. in different seasons were determined.The results showed that,in a year,the content of CPT presented two peaks curve in tender leaves of C. acuminata,which appeared in July and September respectively and reached the highest point in July,while it declined persistently in older leaves;The accumulation of CPT and HCPT presented evident relativity in the different growth stages.

Key words: HPLC, leaves of Camptotheca acuminata, camptothecin, 10-hydroxy-camptothecin, growth stage

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