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    Study on Traditional Medicinal Preparation Technology of Jixiang Cough Ointment
    LI Jin, LUO Yuanqiang, WU Yizhen, PENG Yong, HUANG Li
    Journal of Jishou University(Natural Sciences Edition)    2022, 43 (5): 83-88.   DOI: 10.13438/j.cnki.jdzk.2022.05.013
    Abstract476)      PDF(pc) (414KB)(145)       Save
    The standard for traditional medicinal preparation technology of Jixiang cough ointment has been established.The extraction rate (dry extract) reached 96.21% through three times of decoction with drinking water for 2 hours,2 hours,and 1 hour respectively.The extracts were filtered and combined for three times,and concentrated in the low-temperature hot reflux extraction and concentration equipment to obtain clear paste with a relative density of 1.15~1.25.A proper amount of rock sugar was boiled with water to make honeycomb-like syrup.When the relative density of syrup was greater than 1.4 (80 ℃),clear paste was added (the ratio of clear paste to syrup was 1∶1.5),and the paste was collected at normal pressure.The paste was concentrated with relative density 1.25~1.40,with addition of 0.1% potassium sorbate,and then was encapsulated.The extraction,concentration,sugar refining,paste collection,and paste collecting processes of Jixiang cough ointment are compatible with the equipments in the preparation room.It is a traditional Chinese medicinal preparation.The quality of the finished products is stable and meets the requirements,and it can be produced in the hospital preparation room.The preparation process is stable,simple,reproducible,and effective.
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    A Case Analysis of Breast Cancer Patient with Drug-Induced Liver Injury
    PENG Jing, CHEN Chao, LI Min, XU Xingmin, SONG Kui, FU Yilan
    Journal of Jishou University(Natural Sciences Edition)    2022, 43 (5): 89-92.   DOI: 10.13438/j.cnki.jdzk.2022.05.014
    Abstract385)      PDF(pc) (433KB)(112)       Save
    By analyzing the conditions of liver injury,diagnosis and treatment process,medication for a case of breast cancer patient with drug-induced liver injury(DILI),selection of appropriate liver protective drugs in the process of anti-tumor treatment for DILI patients is explored,and the pharmaceutical care effect of clinical pharmacists on DILI patients is analyzed,which offers reference for the entire treatment cycle for similar cases.
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    A Case Report of Thrombocytopenia Caused by Linezolid
    LONG Xiaokang, PENG Xin, XU Xingmin, SONG Kui, ZHENG Yunfei, CHEN Chao, LI Ming
    Journal of Jishou University(Natural Sciences Edition)    2022, 43 (5): 93-96.   DOI: 10.13438/j.cnki.jdzk.2022.05.015
    Abstract406)      PDF(pc) (372KB)(64)       Save
    This paper reports a case of linezolid induced thrombocytopenia,and introduces the mechanism,risk factors,prevention and treatment.According to the analysis of adverse reaction correlation evaluation,this case of thrombocytopenia is probably related to the use of linezolid.At present,the mechanism of linezolid induced thrombocytopenia is still unclear.Long-term medication,renal dysfunction,and low platelet count at baseline are independent risk factors.Clinical pharmacists should strengthen pharmaceutical care,improve early prevention awareness,and avoid adverse drug reactions.
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