Journal of Jishou University(Natural Sciences Edition) ›› 2022, Vol. 43 ›› Issue (5): 93-96.DOI: 10.13438/j.cnki.jdzk.2022.05.015

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A Case Report of Thrombocytopenia Caused by Linezolid

LONG Xiaokang,PENG Xin,XU Xingmin,SONG Kui,ZHENG Yunfei,CHEN Chao,LI Ming   

  1. (1.Xiangxi Autonomous Prefecture People's Hospital,Jishou 416000,Hunan China;2.Jishou University School of Medicine,Jishou 416000,Hunan China)
  • Online:2022-09-25 Published:2023-01-11

Abstract: This paper reports a case of linezolid induced thrombocytopenia,and introduces the mechanism,risk factors,prevention and treatment.According to the analysis of adverse reaction correlation evaluation,this case of thrombocytopenia is probably related to the use of linezolid.At present,the mechanism of linezolid induced thrombocytopenia is still unclear.Long-term medication,renal dysfunction,and low platelet count at baseline are independent risk factors.Clinical pharmacists should strengthen pharmaceutical care,improve early prevention awareness,and avoid adverse drug reactions.

Key words: linezolid, thrombocytopenia, antimicrobial therapy, adverse drug reaction

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