journal6 ›› 2011, Vol. 32 ›› Issue (5): 103-106.

• Medical Science • Previous Articles     Next Articles

Cardiovascular Effects and Mechanisms of Matrine


  1. (Shanghai JiaoTong University,Shanghai 200025,China)
  • Online:2011-09-25 Published:2012-04-06

Abstract: The matrine-type of alkaloids,a kind of natural product,which mostly exist in leguminous plants are of various pharmacological activities.Matrine attributes to treating those diseases in cardiovascular system.Previous studies has indicated that the functions of matrine on cardiovascular system contain anti-arrhythmic,anti-chronic cardiac insufficiency,anti-fiberization etc,and explained the mechanisms of those activities.This article intends to summarize the research progress of matrine’s effects on cardiovascular system and its mechanisms in recent 10 years.The research in this paper indicates that matrine exerts its pharmacological activities by its effects on ion channel,active protein and signal transduction pathway.

Key words: matrine, cardiovascular, pharmacology

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