Abstract: Laboratory synthesis of 1-n-butylcyclohexanol was designed. The detail procedure was that Grignard reagent was prepared by 1-butane bromide reaction with Magnesium, and then 1-n-butyl-cyclohexanol was synthesized by the reaction of Grignard reagent prepared with cyclohexanone. The reaction conditions were investigated. The results show that the pretreatment of rod magnesium has little effect on the productivity, the optical reaction time of the Grignard reaction is 50 min with the corresponding yield being approximately 50.0 %，and this experiment can be done in 5 h.

Key words: 1-n-butylcyclohexanol, Grignard reagent, cyclohexanone, n-butyl bromide