Abstract: CT images of 66 normal neonates and 71 neonates with HIE were analyzed statisctically.The results showed that in normal neonates the alba density was slightly low with  CT values of 19.0~ 28.0 Hu and the margin of it showed the "maple "sign. The lowest values of alba in 95.4%(63/66)normal neonates were 20Hu. CT values of normal ectocinarea were 27.6~39.0 Hu. Most CT values of low density leisions of alba with HIE were lower than 17Hu.The margins of them showed "petal" sign.The results demenstrated that CT  was more valuable for early diagnosis of HIE and helpful for protocle making.Moreover,CT grade according to cerebral edema with or without cerebral ventricle changes or intracalvalium haemorrhage has more advantages.

Key words: neonates, hypoxic-ischemic encephalopathy, spiral computed tomography