Abstract: Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol using p-toluene sulphonic acid  as catalysts without  solvent under microwave irradiation.The effects of reactant ratio,amount of catalyst,microwave irradiation power and microwave irradiation time on the yield of cyclohexanone 1,2-propanediol ketal were studied.The optimal conditions for the synthesis were as follows:n(cyclohexanone)∶n(1,2-propanediol)=1∶1.6,mass ratio of catalyst to reactant 0.5%,microwave irradiation power 350W and radiation time 3min.Under these conditions,the yield of cyclohexanone 1,2-propanediol ketal could reach 78.0%.

Key words: cyclohexanone 1,2-propanediol ketal, p-toluene sulphonic acid, microwave synthesis