Abstract: Objective To study the relation of serum leptin and liver function in patients with alcoholic liver disease(ALD).Methods The levels of serum leptin and liver function were measured by radioimmunoassay(RIA)  and the sequential multiple autoanalyzer in patients with ALD,including 22 alcoholic fatty liver(AFL),11 alcoholic hepatitis(AH),13 alcoholic cirrhosis(AC)and 30 healthy control groups.Results The levels of serum leptin in patients with ALD were higher than that of normal control group.The levels of leptin were significantly related to liver function in patients with ALD.Conclusion The levels of serum leptin may be an indication of liver function in patients with ALD.

Key words: alcoholic liver disease(ALD), leptin, liver function