journal6 ›› 2001, Vol. 22 ›› Issue (4): 23-28.

• Doctoral Forum • Previous Articles     Next Articles

Manufacture of the Gelatin- sodium Carboxymethyl Cellulose Microcapsule Containing Testosterone for Fish


  1. ( Feed Science Institute of Zhejiang University ,Hangzhou 310029, Zhejinag China)
  • Online:2001-12-15 Published:2013-01-05

Abstract: The manufacture of microcapsule using Gelatin-sodium Carboxymethyl Cellulose as coating material and testosterone as core material(TGM) is introduced. The average diameters of microcapsule was determined to be 29. 5 μm.The mean drug loading in microcapsule was assayed to be ( 71. 8±0.9) % for TGM. In vitrorelease show after burst release in first few days, the drugrelease from microcapsule was obeyed zero-order. The testees of male Japanese eel were achieved maturation by injection TGM at the interval of 25 d. The mean GSI of female eel were reached 19. 7% by injection TGM four times at the interval of 25 d.

Key words: gelatin-sodium carboxymethyl cellulose, microcapsule, testosterone, Japanese eel

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