Implications of  Self-Healing for the Research and Development of New Drugs and New Treatment Technologies for Diseases

doi:10.13438/j.cnki.jdzk.2024.06.011

Abstract

Abstract: In order to explore a new path for research and development of new drugs and new treatment technologies for diseases,literatures relating to self-healing from Google Scholar,PubMed database,and Websites was retrieved and analyzed.It can be found that many human diseases show the possibility of self-healing.According to the above findings,a novel insight into developing new drugs and new treatment technologies for diseases is proposed based on triggering self-healing.

Key words: self-healing of disease, new drugs, new treatment technologies for diseases, research and development

YANG Maosheng. Implications of Self-Healing for the Research and Development of New Drugs and New Treatment Technologies for Diseases[J]. Journal of Jishou University(Natural Sciences Edition), 2024, 45(6): 72-76.

References

[1] CHU Ting,YANG Maosheng.Disease is Essentially a Biodiversity:A Hypothesis[J].Medical Hypotheses,2022,162:110838.DOI:10.1016/j.mehy.2022.110838.
[2] FANU JAMES LE.The Rise and Fall of Modern Medicine[M].First Edition.New York:Carroll & Graf Publishers,2000.
[3] O'REGAN BRENDAN,HIRSHBERG CARYLE.Spontaneous Remission:An Annotated Bibliography[M].First Edition.California:Institute of Noetic Sciences,1993.
[4] HANDLEY W SAMPSON.A Lecture on the Natural Cure of Cancer[J].British Medical Journal,1909,1(2514):582-589.
[5] ROTHMAN S,SMILJANIC A,SHAPIRO A L,et al.The Spontaneous Cure of Tinea Capitis in Puberty[J].Journal of Investigative Dermatology,1947,8(2):81-98.
[6] HARROW BENEDICT R.Spontaneous Cure of Prostatic Fibroadenoma by an Abscess[J].Journal of Urology,1967,97(6):1068-1069.
[7] DEVADIGA K V,MATHAI K V,CHANDY J.Case Reports and Technical Notes Spontaneous Cure of Intracavernous Aneurysm of the Internal Carotid Artery in a 14-Month-Old Child[J].Journal of Neurosurgery,1969,30(2):165-168.
[8] BROWNE S G.Self-Healing Leprosy:Report on 2749 Patients[J].Leprosy Review,1974,45(2):104-111.
[9] CHALLIS G B,STAM H J.The Spontaneous Regression of Cancer.A Review of Cases from 1900 to 1987[J].Acta Oncologica,1990,29(5):545-550.
[10] HEJMADI M.Why do Some Cancers Suddenly Disappear? [EB/OL].[2024-06-10].http:∥medicalxpress.com/news/2016-06-cancers-suddenly-treatment.html.
[11] ELDRIDGE LYNNE.Spontaneous Remission of Cancer Incidence and Causes[EB/OL].[2024-06-10].https:∥www.verywellhealth.com/spontaneous-remission-of-lung-cancer-a-rare-miracle-3971875?print.
[12] SPALLONE ALDO,PERESEDOV VYACHESLAV V,KANDEL EDWARD I.Spontaneous Cure of Ruptured Intracranial Arterial Aneurysms[J].Surgical Neurology,1981,16(5):367-370.
[13] BENCINI PIER L,SALA FRANCESCO,VALERIANI DANIELE,et al.Self-Healing Pseudoangiosarcoma.Unusual Vascular Proliferation Resembling a Vascular Malignancy of the Skin[J].Archives of Dermatology,1988,124(5):692-694.
[14] KALIALIS LOUISE V,DRZEWIECKI KRZYSZTOF T,MOHAMMADI MAHIN,et al.Spontaneous Regression of Metastases from Malignant Melanoma:A Case Report[J].Melanoma Research,2008,18(4):279-283.
[15] MARTN J M,JORD E,CALDUCH L,et al.Self-Healing Generalized Infantile Myofibromatosis[J].Journal of the European Academy of Dermatology and Venereology,2008,22(2):236-238.
[16] AL-HADAD I,KOTECHA S,WEBSTER K.Multiple Self-Healing Squamous Cell Carcinomas of the Face[J].British Journal of Oral and Maxillofacial Surgery,2009,47(8):635-637.
[17] YAMAMOTO MASAKI,IIZUKA SHUHEI,OTSUKI YOSHIRO,et al.Spontaneous Regressions in Non-Small Cell Lung Cancer with Different Clinical Outcomes[J].International Journal of Surgery Case Reports,2022,92:106812.DOI:10.1016/j.ijscr.2022.106812.
[18] KONGWATTANANON WIJAK,KUMAR AMAN,SIMARD JILLIAN,et al.Secondary Vitreoretinal Lymphoma with Spontaneous Regression[J].American Journal of Ophthalmology Case Reports,2022,25:101357.DOI:10.1016/j.ajoc.2022.101357.
[19] CURRY LAUREN,LIMAYE WARDA,RAMJEESINGH R.Spontaneous Regression of Metastatic Hepatocellular Carcinoma Following 3 Weeks of Lenvatinib[J].BMJ Case Reports,2022,15(2):e247212.DOI:10.1136/bcr-2021-247212.
[20] YANG Bo,LI Danfeng,XIAO Jun.Spontaneous Regression of an Isolated Retinal Astrocytic Hamartoma in a Newborn:A Case Report[J].BMC Ophthalmology,2023,23(1):395.DOI:10.1186/s12886-023-03135-5.
[21] SHUTTLEWORTH PAUL W,ULLAH SANA,SCOTT MICHAEL,et al.Complete Spontaneous Regression of Colorectal Cancer:A Report of Two Cases[J].Cureus,2023,15(5):e39128.DOI:10.7759/cureus.39128.
[22] D'ALESSANDRIS NICOLETTA,SANTORO ANGELA,ARCIUOLO DAMIANO,et al.What can Trigger Spontaneous Regression of Breast Cancer?[J] Diagnostics (Basel),2023,13(7):1224.DOI:10.3390/diagnostics13071224.
[23] GONZLEZ-ENSEAT M ANTONIA,VICENTE M ASUNCION,CASTELL NURIA,et al.Self-Healing Infantile Familial Cutaneous Mucinosis[J].Pediatric Dermatology,1997,14(6):460-462.
[24] COWEN EDWARD W,SCOTT GLYNIS A,MERCURIO MARY GAIL.Self-Healing Juvenile Cutaneous Mucinosis[J].Journal of the American Academy of Dermatology,2004,50(5):97-100.
[25] SPERBER BRIAN R,ALLEE JULIE,JAMES WILLIAM D.Self-Healing Papular Mucinosis in an Adult[J].Journal of the American Academy of Dermatology,2004,50(1):121-123.
[26] LAUT-LABRZE CHRISTINE,BORALEVI FRANCK,CONY MARIANE,et al.Self-Healing Congenital Verruci-form Hyperkeratosis[J].American Journal of Medical Genetics Part A,2004,130A(3):303-306.
[27] ROBATI R M,MALEKZAD F,SAEEDI M,et al.Multiple Self-Healing Scarring Lesions on the Face[J].Clinical and Experimental Dermatology,2011,36(4):443-444.
[28] JIN Shuang,LIU Linxi,LI Rong,et al.A Rare Case of Self-Healing Giant Condyloma Acuminatum[J].Dermatologic Therapy,2022,35(1):e15189.DOI:10.1111/dth.15189.
[29] HASHIMOTO KEN,GRIFFIN DARRELL,KOHSBAKI MASATOSHI.Self-Healing Reticulohistiocytosis:A Clinical,Histologic,and Ultrastructural Study of the Fourth Case in the Literature[J].Cancer,1982,49(2):331-337.
[30] BELHADJALI H,MOHAMED M,MAHMOUDI H,et al.Self-Healing Langerhans Cell Histiocytosis (Hashimoto-Pritzker Disease):Two Tunisian Cases[J].Acta Dermatovenerologica Alpina Pannonica et Adriatica,2008,17(4):188-192.
[31] SAPP J PHILIP,STARK MICHELLE L.Self-Healing Traumatic Bone Cysts[J].Oral Surgery,Oral Medicine,and Oral Pathology,1990,69(5):597-602.
[32] YUE Ping,MENG Wenbo,LUO Zhiwen,et al.Unusual Self-Healing of a Traumatic Pancreatic Fistula that Persisted for 16 Months[J].Turkish Journal of Gastroenterology,2018,29(1):138-139.
[33] BANERJEE ABHISHEK,MISRA SATYA RANJAN,KUMAR VIVEK,et al.Traumatic Ulcerative Granuloma with Stromal Eosinophilia (Tugse):A Rare Self-Healing Oral Mucosal Lesion[J].BMJ Case Reports,2021,14(8):e245097.DOI:10.1136/bcr-2021-245097.
[34] FRANCOLINO SONIA S,ANTUNES ANTONIO FERNANDEZ,TALICE RODOLFO,et al.New Evidence of Spontaneous Cure in Human Chagas' Disease[J].Revista da Sociedade Brasileira de Medicina Tropical,2003,36(1):103-107.
[35] DIAS JOO CARLOS PINTO,DIAS EMMANUEL,FILHO OLINDO M,et al.Further Evidence of Spontaneous Cure in Human Chagas Disease[J].Revista da Sociedade Brasileira de Medicina Tropical,2008,41(5):505-506.
[36] ROSSETTO ANDR LUIZ,CRUZ ROSANA C BELLA.Spontaneous Cure in a Case of Tinea Nigra[J].Anais Brasileiros de Dermatologia,2012,87(1):160-162.
[37] CASADO CONCEPCION,GALVEZ CRISTINA,PERNAS MARIA,et al.Permanent Control of HIV-1 Pathogenesis in Exceptional Elite Controllers:A Model of Spontaneous Cure[J].Scientific Reports,2020,10(1):1902.DOI:10.1038/s41598-020-58696-y.
[38] ALAM SARAH,KUBIHAL SURAJ,GOYAL ALPESH,et al.Spontaneous Remission of Acromegaly After Pituitary Apoplexy in a Middle-Aged Male[J].Ochsner Journal,2021,21(2):194-199.
[39] NODA RYUICHI,AKABANE ATSUYA,KAWASHIMA MARIKO,et al.Spontaneous Regression of an Unruptured Arteriovenous Malformation due to Drainer Vein Thrombosis in a Patient with Protein S Deficiency:A Case Report and Literature Review[J].NMC Case Report Journal,2023,10:221-226.
[40] IAMPREECHAKUL PRASERT,CHUNTAROJ SONGPOL,WATTANASEN YODKHWAN,et al.Spontaneous Regression of Extradural High-Flow Vascular Malformation in Spinal Arteriovenous Metameric Syndrome (Sams):A Unique Case Report[J].Surgical Neurology International,2023,14:163.DOI:10.25259/SNI_4_2023.
[41] ALJOHANI SARA,ALSHANQITI MARYAM,ALZAHRANI MOAJEB.Unexpected Recovery:A Report on the Spontaneous Regression of a Herniated Cervical Disc[J].Cureus,2023,15(7):e41429.DOI:10.7759/cureus.41429.
[42] BUCHLER TOMAS,FISER LUKAS,BENESOVA JAROSLAVA,et al.Spontaneous Regression of Metastatic Renal Cell Carcinoma After SARS-CoV-2 Infection:A Report of Two Cases[J].Current Oncology,2021,28(5):3403-3407.
[43] SOUSA LUANA GUIMARAES DE,MCGRAIL DANIEL J,LI Kaiyi,et al.Spontaneous Tumor Regression Following COVID-19 Vaccination[J].Journal for Immunotherapy of Cancer,2022,10(3):e004371.DOI:10.1136/jitc-2021-004371.
[44] CHU Ting,YANG Maosheng.Cellular Transformation may be a Most Promising Approach for the Treatment of Diseases:A Hypothesis[J].Medical Hypotheses,2022,166:110917.DOI:10.1016/j.mehy.2022.110917.

Implications of Self-Healing for the Research and Development of New Drugs and New Treatment Technologies for Diseases

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