journal6 ›› 2015, Vol. 36 ›› Issue (3): 90-93.DOI: 10.3969/j.cnki.jdxb.2015.03.019

• Biological resources • Previous Articles     Next Articles

Antitoxic Effect of Extracts of Tripterospemum Cordatum Against  Deinagkistrodon Acutus Snake Venom

 ZHOU  Luo-Qin, TIAN  Hong-Xian   

  1. (College of Biology & Environmental Science,Jishou University,Jishou 416000,Hunan China)
  • Online:2015-05-25 Published:2015-06-03

Abstract: The antitoxic effect of Tripterospemum cordatum aqueous extracts against Deinagkistrodon acutus snake venom is researched.The BACA/C mice were divided into five group according to the dosage of Tripterospemum cordatum aqueous extracts applied:low dosage,middle dosage,high dosage,blank group and model group,each group of health conditions being observed after 7-days intra-gastric administration.For the last time of administration,each group was intraperitoneally injected with Agkistrodon acutus snake venom after one hour later,then the mice’s poisoning performance was observed and the death rate was calculated,and each group of mice’s tissue bleeding,death and ulceration compared.The results showed that the aqueous extract of Tripterospemum cordatum at the low dosage,middle dosage and high dosage all reduced the mortality caused by Agkistrodon acutus snake venom poisoning and relieved some symptoms;with the increase of the dosage the symptoms decreased significantly,and the protection effect on the tissue was especially apparent.It can be concluded that the aqueous extract of Tripterospemum cordatum has antitoxic effect against Agkistrodon acutus snake venom and decrease the toxicity.

Key words: extracts of Tripterospemum, Deinagkistrodon acutus, antitoxic, protective rate

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