journal6 ›› 2002, Vol. 23 ›› Issue (3): 36-39.

• Doctoral Forum • Previous Articles     Next Articles

Study of Gene Expression of p16 With in Situ Hybridization Technique


  1. (1.The Biology Department of College of Life Science and Chemistry,Jishou University,Jishou 416000,Hunan China;2.The Biology Department of College of Life Science and Chemistry,Yunnan University,Kunming 650091,China;3.College of Bioformatic,Chongqing of Post and Telecommunications University,Chongqing 400065,China)
  • Online:2002-09-15 Published:2013-01-05

Abstract: Using in situ hybridization technique with Dig labeled probe,the expression of p16 gene in mice's embryo development has been studied in this thesis.The results can be summarized as fellows: p16 gene does not take part in the formation of organ proimordia during the development of embryo of age 9ds and 10ds.It takes part in the further process of organ differentiation (concerned organs include eyes,brain,heart,lung,backbone and cranium viscerale,except liver); There are different regulation mechanisms in the different organs.

Key words: in situ hybridization;p16;cell cycle regulation; , gene expression

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