Abstract: This paper studies the association rules data mining,the concept of interestingness and  algorithm design based on the concept.Taking vocational college’s achievement database for processing object，this paper analyzes the association rules of courses;and with interestingness as constraint conditions,deceptive invalid association rules are eliminated,and some reliable interesting association rules of courses are discovered.This paper provides reference for vocational college curriculum design and syllabus revision，and it also verifies the validity of the algorithm.

Key words: data mining, association rules, interestingness, course-setting