Abstract: Objective:To explore the correlation between serum selenium and gestational diabetes mellitus.Methods:From March 2020 to September 2021,360 pregnant women were selected as subjects according to the inclusion criteria,180 of whom were normal physical examination subjects with negative GDM diagnosis and were classified as control group,and 180  with positive GDM diagnosis received hospitalization and were classified as observation group.Methods:Selenium levels in different pregnancy periods of the same group and the selenium levels in same pregnancy period of the two groups were compared.Pregnancy outcomes and neonatal outcomes of the two groups were compared.Results:The serum selenium level of pregnant women in the third trimester was lower than that in the middle and early trimesters in the two groups (P<0.05),and the serum selenium level of pregnant women in the second trimester was lower than that in the early trimesters in the observation group (P<0.05).The incidence of adverse pregnancy outcomes and adverse neonatal outcomes in the observation group were higher than those in the control group.Conclusion:There is a strong correlation between serum selenium and gestational diabetes mellitus,and it is of positive significance for pregnant women to supplement selenium by detecting trace elements during pregnancy.

Key words: selenium, gestational diabetes mellitus, correlation