Journal of Jishou University(Natural Sciences Edition)

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Therapy Function of Aqueous Extract from Pteridium Aquilinum on Constipated Mice

LI Lihua,SHI Guang,DUAN Zhen,LV Jiangming,TIAN Xiangrong   

  1. (1. 1.Key Laboratory of Plant Resources Conservation and Utilization (Colleges and Universities of Hunan Province),Jishou University,Jishou 416000,Hunan China;2.College of Medicine,Jishou University,Jishou 416000,Hunan China)
  • Online:2016-05-25 Published:2016-06-24


Mice treated with sucralfate and Fosson were used as animal model to test the therapy function of aqueous extract of different concentration (20,40,60 g/kg) from fern on constipation.Results showed that,compared with the sucralfate-treated group (negative control),the groups treated with fern water extract displayed obvious therapy improvement on intestine propulsion (SIP),first defecation time,faeces properties and 4 h defecation grain number and mass.On the other hand,compared with the Fosson-therapy group (positive control),the middle dose group demonstrated almost the same effect on constipation therapy;but as for first defecation time,the high dose group treated with aqueous extract ((17.200 0±3.938 4)min)  was obviously sooner than the Fosson treated group ((26.800 0±3.881 6)min).And as for SIP,middle and low dose groups treated with fern aqueous extract ((34.000 5±6.057 5)%,(31.529 8±4.204 8)%) were obviously less than Fosson therapy group,but the high dose group ((41.9481±4.2194)%) showed almost no difference with Fosson therapy group(43.057 9±6.308 4)%).

Key words: Pteridium aquilinum, aqueous extract, constipation, therapy, mouse

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