Abstract: Obejctive To analyze and compare the effect of different courses of retroauricular injection of methylprednisolone on sudden sensorineural hearing loss. Methods 134 patients with sudden sensorineural hearing loss who were hospitalized from February 2019 to December 2019 were randomly divided into 3 groups according to the order of admission. 45 patients in group A were injected with methylprednidone 40 mg retroauricular, a total of 3 times. 45 patients in group B, a total of 5 times. 44 patients in group C, a total of 7 times. After thetreatment, pure-tone audiometry was re-examined to compare the efficacy of the three groups. Results the effective rate of group A was 64.4%, the average threshold of hearing increased 20.2±17.5 dB HL, the effective rate of group B was 66.7%, the average threshold of hearing increased 20.9±16.7 dB HL, the effective rate of group C was 68.1%, the average threshold of hearing increased 19.6±17.9 dB HL, there was no statistical significance. Conclusion there is no significant difference in the efficacy of retroauricular injection of methylprednil in the treatment of sudden sensorineural hearing loss, a short course of retroauricular injection of methylprednil can achieve the purpose of treatment.

Key words: sudden sensorineural hearing loss, methylprednidone, retroauricular injection, course of treatment, therapeutic effect