不同疗程耳后注射甲强龙治疗突发性聋的疗效

doi:10.13438/j.cnki.jdzk.2021.06.012

吉首大学学报（自然科学版） ›› 2021, Vol. 42 ›› Issue (6): 73-79.DOI: 10.13438/j.cnki.jdzk.2021.06.012

不同疗程耳后注射甲强龙治疗突发性聋的疗效

胡娅琴，干强，廖修富，陈红江

（重庆市人民医院耳鼻咽喉头颈外科,重庆 400013）

出版日期:2021-11-25 发布日期:2022-01-21
通讯作者: 陈红江（1980—），男，重庆市人，硕士，中国科学院大学重庆医院（重庆市人民医院）副主任医师，主要从事耳科学基础与临床研究.
作者简介:胡娅琴（1985—），女，重庆市人，中国科学院大学重庆医院（重庆市人民医院）主治医师，硕士，主要从事听力言语、毛细胞及前庭功能研究
基金资助:
重庆市科卫联合中青年医学高端人才资助项目（ZQNYXGDRCXM20192106）；重庆市科卫联合面上资助项目（2021MSXM048）

Treatment of Sudden Sensorineural Hearing Loss with Methylprednidone of Retroauricular Injection: Effect of Different Courses of Treatment

HU Yaqin，GAN Qiang，LIAO Xiufu，CHEN Hongjiang

(Department of Otolaryngology Head and Neck Surgery, Chongqing General Hospital, Chongqing 400013, China)

Online:2021-11-25 Published:2022-01-21

摘要/Abstract

摘要：目的分析和比较突发性聋患者采用不同疗程耳后注射甲强龙激素治疗突发性聋的疗效差异.方法选取2019年2月至2019年12月在重庆市人民医院耳鼻咽喉头颈外科就诊并行住院治疗的突发性聋患者共134例，采用数字随机表法将患者分为3组，A组45例，行耳后注射甲强龙，一共3次；B组45例，行耳后注射甲强龙，一共5次；C组44例，行耳后注射甲强龙，一共7次；疗程结束后复查纯音测听，比较3组患者的治疗效果.结果 A组总有效率为64.4%，听阈提高值为20.2±17.5 dB HL；B组总有效率为66.7%，听阈提高值为20.9±16.7 dB HL；C组总有效率为68.1%，听阈提高值为19.6±17.9 dB HL，三组患者的疗效指标差异无统计学意义（P>0.05）.结论对突发性聋患者采用不同疗程的耳后注射甲强龙治疗所获得的近期治疗效果比较无显著差距，因此，3个疗程的耳后注射甲强龙即可达到治疗目的.

关键词： 突发性聋, 甲强龙, 耳后注射, 疗程, 疗效

Abstract: Obejctive To analyze and compare the effect of different courses of retroauricular injection of methylprednisolone on sudden sensorineural hearing loss. Methods 134 patients with sudden sensorineural hearing loss who were hospitalized from February 2019 to December 2019 were randomly divided into 3 groups according to the order of admission. 45 patients in group A were injected with methylprednidone 40 mg retroauricular, a total of 3 times. 45 patients in group B, a total of 5 times. 44 patients in group C, a total of 7 times. After thetreatment, pure-tone audiometry was re-examined to compare the efficacy of the three groups. Results the effective rate of group A was 64.4%, the average threshold of hearing increased 20.2±17.5 dB HL, the effective rate of group B was 66.7%, the average threshold of hearing increased 20.9±16.7 dB HL, the effective rate of group C was 68.1%, the average threshold of hearing increased 19.6±17.9 dB HL, there was no statistical significance. Conclusion there is no significant difference in the efficacy of retroauricular injection of methylprednil in the treatment of sudden sensorineural hearing loss, a short course of retroauricular injection of methylprednil can achieve the purpose of treatment.

Key words: sudden sensorineural hearing loss, methylprednidone, retroauricular injection, course of treatment, therapeutic effect

胡娅琴, 干强, 廖修富, 陈红江. 不同疗程耳后注射甲强龙治疗突发性聋的疗效[J]. 吉首大学学报（自然科学版）, 2021, 42(6): 73-79.

HU Yaqin, GAN Qiang, LIAO Xiufu, CHEN Hongjiang. Treatment of Sudden Sensorineural Hearing Loss with Methylprednidone of Retroauricular Injection: Effect of Different Courses of Treatment[J]. Journal of Jishou University(Natural Sciences Edition), 2021, 42(6): 73-79.

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不同疗程耳后注射甲强龙治疗突发性聋的疗效

Treatment of Sudden Sensorineural Hearing Loss with Methylprednidone of Retroauricular Injection: Effect of Different Courses of Treatment

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