不同剂型生脉散对氧自由基清除作用的比较

journal6 ›› 2007, Vol. 28 ›› Issue (3): 123-125.

不同剂型生脉散对氧自由基清除作用的比较

（1.湘潭职业技术学院医学院，湖南湘潭 411100；2.中南大学湘雅医学院，湖南长沙 410078；3.吉首大学医学院，湖南吉首 416000）

出版日期:2007-05-25 发布日期:2012-08-27
作者简介:余庆皋（1955-），男，湖北武汉人，湘潭职业技术学院医学院副教授，主要从事自由基清除剂及高职教学研究.

Comparative Study on the Effect on Removing Oxygen FreeRadicals with Different Forms of Shengmai Power

(1.College of Medical,Xiangtan Vocational & Technical College,Xiangtan 411100,Hunan China;2.Xiangya Medical College,Central South University,Changsha 410078,China;3.College of Medical,Jishou University,Jishou 416000,Hunan China)

Online:2007-05-25 Published:2012-08-27

摘要/Abstract

摘要：研究了生脉注射液、生脉饮、生脉胶囊这3种直接用于临床的成药剂型是否也具有抗氧自由基（羟自由基·OH和超氧阴离子自由基O－2·）作用，并且不同剂型之间是否有差异.用邻二氮菲-Fe2+氧化法测定·OH，用改进的邻苯三酚自氧化法测定O－2·.结果表明，3种剂型生脉散均有清除·OH和O－2·的能力，与对照管比较有高度显著性差异（P＜0.01），各剂型之间无显著性差异（P＞0.05）.

关键词： 生脉注射液, 生脉饮, 生脉胶囊, 氧自由基

Abstract: To study whether the three proprietary forms——Shengmai injection,Shengmai drink,Shengmai capsule,which can be directly used in clinic,have the effect of resistance on oxygen free radical (hydrogen radical ·OH and superoxide anion radical O－2·,whether there are any differences between the three.Mensurate ·OH with the oxidation of phenathroline -Fe2+，mensurate O－2· with improved pyrogallol auto-oxidation.Results shows that all of the three forms of Shengmai power are of the ability of removing ·OH and O－2·;there are not significant differences between the three (P>0.05),but there are significant differences when compared with comparison tube (P<0.01).

Key words: Shengmai injection, Shengmai drink, Shengmai capsule, oxygen free radicals

余庆皋, 王晓春, 钟飞. 不同剂型生脉散对氧自由基清除作用的比较[J]. journal6, 2007, 28(3): 123-125.

YU Qing-Gao, WANG Xiao-Chun, ZHONG Fei. Comparative Study on the Effect on Removing Oxygen FreeRadicals with Different Forms of Shengmai Power[J]. journal6, 2007, 28(3): 123-125.