高山麝病原性阿尔伯蒂埃希氏杆菌（Escherichia  albertii）的发现

doi:10.3969/j.issn.1007-2985.2012.06.022

journal6 ›› 2012, Vol. 33 ›› Issue (6): 95-101.DOI: 10.3969/j.issn.1007-2985.2012.06.022

高山麝病原性阿尔伯蒂埃希氏杆菌（Escherichia albertii）的发现

（1.吉首大学生物资源与环境科学学院，湖南吉首 416000;2.甘肃兴隆山国家级自然保护区管理局，甘肃兰州730117;3.澳大利亚国立大学考古学与人类学系，堪培拉首都领地 2602；4.中央民族大学生命与环境科学学院，北京 100081）

出版日期:2012-11-25 发布日期:2013-01-14

Pathogenic Escherichia Albertii Discovered in the Alpine Musk Deer (Moschus chrysogaster) in China

(1.College of Biology and Environmental Sciences,Jishou University,Jishou 416000,Hunan China;2.The Authority of Xinglongshan National Natural Reserve,Lanzhou 730117,China;3.The School of Archaeology and Anthropology,Australia National University,2602 ACT,Australia;4.College of Life and Environmental Science,Mizu University of China,Beijing 100081,China)

Online:2012-11-25 Published:2013-01-14
About author:DING Yu-jing(1986-)，female,was Born in Hanshou County,Hunan Province.M.D.；Research area are animal ecology and conservation biology
Supported by:
National Natural Scientific Foundation of China (30570279)

摘要/Abstract

摘要：麝是古北界的特有种和我国一级保护动物，具有相当重要的经济价值和物种保护价值.幼麝的高死亡率，特别是由腹泻或肠炎所引起的死亡已经严重地影响着中国养麝业的发展.从甘肃兴隆山养麝场死于消化道疾病的高山麝(Moschus chrysogaster)的肠道内容物中分离出了病原性的肠杆菌.基于形态学、生理生化特征及16SrRNA基因序列的种系遗传学综合分析鉴定其为阿尔伯蒂埃希氏杆菌（Escherichia albertii）.对该菌进行抗生素敏感性检测，结果表明，其对不同的抗生素有不同的敏感性，这可能是麝长期经受少数几种固定的抗生素（如青霉素、四环素）治疗，细菌产生抗性而使抗生素失效所致.建议麝场定期对肠杆菌进行分离、鉴定,选用具有针对性的菌株制作菌苗,配以敏感的药物、中草药添加剂和良好的卫生措施,以控制埃希氏杆菌疾病的发生.

关键词： 高山麝(Moschus chrysogaster), 阿尔伯蒂埃希氏杆菌（Escherichia , albertii）, 消化道疾病

Abstract: Musk deer (Moschus spp.) are peculiar to the Palearctic and of considerable value worldwide.The high mortality-rate of fawns,especially caused by diarrhea or enteritis,has severely hindered the development of Chinese musk deer farming.In this study,two strains of pathogenic Enterobacteriaceae were isolated from the intestinal contents of an Alpine Musk Deer (Moschus chrysogaster) which died from digestive diseases at Xinglongshan Musk Deer Farm,Gansu Province,China.They were identified as strains of Escherichia albertii,based on an integrated analysis of morphological,physiological and biochemical characteristics as well as phylogenetics of genetic sequences 16SrRNA.The results of antibiotic sensitivity tests showed that the sensitivities of the bacteria to different antibiotics varied.This might have resulted from the animal’s long treatment for colibacillosis by a fixed set of antibiotics,including penicillin G and tetracycline,which might have lost efficacy because of bacterial resistance.A feasible approach to controlling colibacillosis in future would be alternative use of antibiotics combined with other preventive measures.

Key words: Alpine Musk Deer（Moschus chrysogaster）；Escherichia albertii, digestive disease

丁宇晶, 刘志霄, 邓凯东, 潘世成, 李泉, 康发功, 张学炎, 张佑祥, 科林·格罗夫斯, 孟秀祥. 高山麝病原性阿尔伯蒂埃希氏杆菌（Escherichia albertii）的发现[J]. journal6, 2012, 33(6): 95-101.

DING Yu-Jing, LIU Zhi-Xiao, DENG Kai-Dong, PAN Shi-Cheng, LI Quan, KANG Fa-Gong, ZHANG Xue-Yan, ZHANG You-Xiang, KE Lin-·Ge-Luo-Fu-Si, MENG Xiu-Xiang. Pathogenic Escherichia Albertii Discovered in the Alpine Musk Deer (Moschus chrysogaster) in China[J]. journal6, 2012, 33(6): 95-101.

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高山麝病原性阿尔伯蒂埃希氏杆菌（Escherichia albertii）的发现

Pathogenic Escherichia Albertii Discovered in the Alpine Musk Deer (Moschus chrysogaster) in China

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