微波辐射下磺酸催化无溶剂合成环己酮1,2-丙二醇缩酮

journal6 ›› 2007, Vol. 28 ›› Issue (6): 102-104.

微波辐射下磺酸催化无溶剂合成环己酮1,2-丙二醇缩酮

(1.湖南师范大学化学化工学院,湖南长沙 410081;2.吉首大学化学化工学院,湖南吉首 416000)

出版日期:2007-11-25 发布日期:2012-06-10
作者简介:章爱华（1969-）,女,湖南泸溪人,湖南师范大学化学化工学院硕士研究生,吉首大学化学化工学院讲师,主要从事有机化学研究.
基金资助:
国家自然科学基金资助项目（20572021）

Solvent-Free Synthesis of Cyclohexanone 1,2-Propanediol Ketal Catalyzed by Sulphonic Acid Under Microwave Irradiation

(1.College of Chemistry and Chemical Engineering,Hunan Normal University,Changsha 410081,Hunan China;2.College of Chemistry and Chemical Engineering,Jishou University,Jishou 416000,Hunan China)

Online:2007-11-25 Published:2012-06-10

摘要/Abstract

摘要：在微波辐射下,对甲苯磺酸作催化剂,不用溶剂合成环己酮1,2-丙二醇缩酮，考察酮醇物质的量比、催化剂用量、微波功率和辐射时间对产品收率的影响.结果表明,合成该缩酮的最佳工艺条件为:n(环己酮)∶n(1,2-丙二醇)=1∶1.6,催化剂用量为反应物总质量的0.5%,辐射功率为350 W,辐射时间为3 min.在此条件下,缩酮收率可达78.0%.

关键词： 环己酮1, 2-丙二醇缩酮, 对甲苯磺酸, 微波合成

Abstract: Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol using p-toluene sulphonic acid as catalysts without solvent under microwave irradiation.The effects of reactant ratio,amount of catalyst,microwave irradiation power and microwave irradiation time on the yield of cyclohexanone 1,2-propanediol ketal were studied.The optimal conditions for the synthesis were as follows:n(cyclohexanone)∶n(1,2-propanediol)=1∶1.6,mass ratio of catalyst to reactant 0.5%,microwave irradiation power 350W and radiation time 3min.Under these conditions,the yield of cyclohexanone 1,2-propanediol ketal could reach 78.0%.

Key words: cyclohexanone 1,2-propanediol ketal, p-toluene sulphonic acid, microwave synthesis

章爱华, 尹笃林, 吴竹青. 微波辐射下磺酸催化无溶剂合成环己酮1,2-丙二醇缩酮[J]. journal6, 2007, 28(6): 102-104.

ZHANG Ai-Hua, YIN Du-Lin, WU Zhu-Qing. Solvent-Free Synthesis of Cyclohexanone 1,2-Propanediol Ketal Catalyzed by Sulphonic Acid Under Microwave Irradiation[J]. journal6, 2007, 28(6): 102-104.