吉首大学学报(自然科学版) ›› 2022, Vol. 43 ›› Issue (4): 87-91.DOI: 10.13438/j.cnki.jdzk.2022.04.015

• 医药科学 • 上一篇    下一篇

傣药“小鱼眼草”化学成分的研究

张悦,魏华,曹新杰,刘红玉   

  1. (1.北京市平谷区市场监督管理局检验检测中心,北京 101200;2.吉首大学生物资源与环境科学学院,湖南 吉首 416000;3.吉首大学植物资源保护与利用湖南省高校重点实验室,湖南 吉首 416000)
  • 出版日期:2022-07-25 发布日期:2022-10-28
  • 通讯作者: 刘红玉(1987—),女,北京平谷人,北京市平谷区市场监督管理局检验检测中心主管药师,主要从事中药资源和药品质量研究.E-mail:liuhongyupg@126.com.
  • 作者简介:张悦(1986—),男,北京平谷人,北京市平谷区市场监督管理局检验检测中心主管药师,理学学士,主要从事中药化学和中药质量标准研究

Chemical Constituentsfrom the Aerial Partsof Dichrocephala benthamii

ZHANG Yue,WEI Hua,CAO Xinjie,LIU Hongyu   

  1. (1.Inspection and Testing Center of Market Regulation Administration of Pinggu District,Beijing 101200,China;2.College of Biology and Environmental Science,Jishou 416000,Hunan China;3.Key Laboratory of Hunan Provincial University for Protection and Utilization of Plant Resources,Jishou 416000,Hunan China)
  • Online:2022-07-25 Published:2022-10-28

摘要:目的探究傣药“小鱼眼草”的化学成分.方法采用各种柱色谱技术对小鱼眼草的乙醇提取物进行分离纯化,采用波谱技术结合化学方法进行结构鉴定.结果从小鱼眼草全草提取物中分离得到了15个化合物,包括6个生物碱类,5个萜类,2个黄酮类和3个酚酸类,分别鉴定为胡椒碱(1)、辣椒碱(2)、二氢辣椒碱(3)、3-吲哚甲酸乙酯(4)、3-吲哚甲酸甲酯(5)、3-甲酰基吲哚(6)、pomolic acid(7)、floridiolide A(8)、16-methoxycleroda-3,13-dien-15,16-olide-18-oic acid(9)、16-ethoxycleroda-3,13-dien-15,16-olide-18-oic acid(10)、木栓酮(11)、山奈酚(12)、槲皮素(13)、syringenin isovalerate(14)、没食子酸(15).结论化合物1~12、14为首次从该植物中分离得到.

关键词: 傣药, 小鱼眼草, 化学成分

Abstract: The chemical composition of Dai Medicine Dichrocephala benthamii has been studied.The ethanol extract in Dichrocephala benthamii  was isolated and purified by silica gel chromatography repeatedly,and the structures were identified by spectral analysis and chemical methods.Results showed that fifteen compounds were isolated from the ethanol extraction of Dichrocephala benthamii and the structures were identified as piperine (1),capsaicin (2),dihydrocapsaicin(3),1H-indole-3-carboxylic acid,ethyl ester(4),1H-indole-3-carboxylic acid,methyl ester (5),3-formylindole (6),pomolic acid (7),floridiolide A (8),16-methoxycleroda-3,13-dien-15,16-olide-18-oic acid (9),16-ethoxycleroda-3,13-dien-15,16-olide-18-oic acid (10),friedelin (11),Kaempferol (12),quercetin (13),syringenin isovalerate (14),gallic acid (15).It can be concluded that compounds 1-12,14 were obtained from the genus of Dichrocephala for the first time.

Key words: Dai medicine, D. benthamii, chemical composition

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