%0 Journal Article %A PENG Yingfu %A GAO Hui %T Regulation of ATGL Activity and the Relation to Cardiac Hypertrophy %D 2016 %R 10.3969/j.cnki.jdxb.2016.05.020 %J Journal of Jishou University(Natural Sciences Edition) %P 85-90 %V 37 %N 5 %X

Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme of TG hydrolysis.There is high expression in adipose,liver,heart,and so on. ATGL knockout can result in bulks of triglyceride accumulation and induce significant cardiac hypertrophy in mice or rats. This review focuses on the regulation of ATGL activity and expression and how its dysfunction results in cardiac hypertrophy.

%U https://zkxb.jsu.edu.cn/EN/10.3969/j.cnki.jdxb.2016.05.020