Optimization of the Adsorption Technology of the Total Flavones from Hypericum Japonicum by Response Surface Methodology

doi:10.3969/j.issn.1007-2985.2012.06.021

Abstract

Abstract: With hypericum japonicum as material,adsorption technology of macroporous resin on the total flavones was optimized with ethanol concentration,adsorption temperature and adsorption time as influencing factors and the adsorption rate of total flavones as response value.The mathematical model was established according to Box-Behnken design method,and response surface of the experiment result was analysed.The results showed that adsorption rate of the total flavones was 87.14% with 12% ethanol as solvent at 28 ℃ for 36 min.

Key words: response surface methodology, hypericum japonicum, total flavones, adsorption

YANG Jia-Yu, XU Yong-Wei, SUN Ya-Li, ZHANG Zhen-Zhen, LI Xue-Feng, OuYang-Yu-Zhu . Optimization of the Adsorption Technology of the Total Flavones from Hypericum Japonicum by Response Surface Methodology[J]. journal6, 2012, 33(6): 89-94.

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